Results 141 to 150 of about 4,411 (173)
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MAMPs: A devil tamed becomes an angel
Cell Host & Microbe, 2023Symbiotic microorganisms modulate systemic immunity with unclear mechanisms. In this issue of Cell Host & Microbe, Clarke and colleagues uncover a coherent mechanism where the systemic spread of Firmicutes cell wall glycoconjugates enhances global immune fitness while simultaneously being delicately controlled to prevent systemic inflammation.
Huayuan, Tang, Lin, Wu
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Metabolism-Associated Molecular Patterns (MAMPs)
Trends in Endocrinology & Metabolism, 2020Metabolic diseases pose a tremendous health threat in both developed and developing countries. The pathophysiology of metabolic diseases is complex but has been shown to be closely associated with sterile inflammation, which is initiated by various danger molecules derived from metabolic overload, such as oxidized low-density lipoproteins (OxLDLs ...
Xu, Wang +4 more
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Phospholipase C2 Affects MAMP-Triggered Immunity by Modulating ROS Production [PDF]
Plant Physiology, 2017 The activation of phosphoinositide-specific phospholipase C (PI-PLC) is one of the earliest responses triggered by the recognition of several microbe-associated molecular patterns (MAMPs) in plants. The Arabidopsis (Arabidopsis thaliana) PI-PLC gene family is composed of nine members.
Daniel Couto +2 more
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Active DNA demethylation regulates MAMP-triggered immune priming in Arabidopsis
Journal of Genetics and Genomics, 2022Plants recognize microbe-associated molecular patterns (MAMPs) to activate immune responses and defense priming to defend against pathogen infections. Transcriptional regulation of gene expression is crucial for plant immunity and is mediated by multiple factors, including DNA methylation.
Mengling Huang +8 more
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Spatial IMA1 regulation restricts root iron acquisition on MAMP perception
NatureIron is critical during host-microorganism interactions1-4. Restriction of available iron by the host during infection is an important defence strategy, described as nutritional immunity5. However, this poses a conundrum for externally facing, absorptive tissues such as the gut epithelium or the plant root epidermis that generate environments that ...
Matthieu Pierre Platre +2 more
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MAPK Assays in Arabidopsis MAMP-PRR Signal Transduction
2017Activation of MAPK (Mitogen-Activated Protein Kinase) cascades after MAMP (Microbe-Associated Molecular Pattern) perception through PRR (Pattern Recognition Receptor) is one of the first conserved responses when plants encounter microbial organisms. Phosphorylation of various cellular factors in the MAMP-PRR pathway by MAPK cascades is critical for ...
Hoo Sun, Chung, Jen, Sheen
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Bacteria and MAMP-induced morphogenesis of the immune system
Current Opinion in Immunology, 2010To metazoans, bacteria are more than just potential pathogens. Many examples now document the role of bacterial symbionts in complementing the host for its full development and increasing its digestive and protective functions. Here, we discuss the role of Gram-negative bacteria in the development of intestinal lymphoid tissues and the impact of ...
Eberl, G, & I.G. Boneca
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MAMPs and MIMPs: proposed classifications for inducers of innate immunity
Molecular Microbiology, 2006Summary Plants encode a sophisticated innate immune system. Resistance against potential pathogens often relies on active responses. Prerequisite to the induction of defences is recognition of the pathogenic threat. Significant advances have been made in our understanding of the non‐self molecules that are recognized by plants and the
David, Mackey, Aidan J, McFall
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MAMP and DAMP signaling contributes resistance to Fusarium graminearum in Arabidopsis
Journal of Experimental Botany, 2021Abstract Plants perceive externally produced microbe-associated molecular patterns (MAMPs) and endogenously produced danger-associated molecular patterns (DAMPs) to activate inducible immunity. While several inducible immune responses have been observed during Fusarium graminearum infection, the identity of the signaling pathways ...
Nimrat Manes +3 more
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Genetic dissection of the maize (Zea mays L.) MAMP response
Theoretical and Applied Genetics, 2017Loci associated with variation in maize responses to two microbe-associated molecular patterns (MAMPs) were identified. MAMP responses were correlated. No relationship between MAMP responses and quantitative disease resistance was identified. Microbe-associated molecular patterns (MAMPs) are highly conserved molecules commonly found in microbes which ...
Xinye Zhang +4 more
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