Results 51 to 60 of about 4,411 (173)

Effects of Methamphetamine on Testes Histopathology and Spermatogenesis Indices of Adult Male Rats [PDF]

Addiction and Health, 2017
Background: Methamphetamine (mAMP) as a recreational drug has devastating effects on the central nervous system (CNS). Several studies have shown that mAMP has inhibitory effects on oogenesis and spermatogenesis, and causes impaired fertility. This study
Arezoo Saberi, Gholamreza Sepehri, Zohreh Safi, Behzad Razavi, Faranak Jahandari, Kouros Divsalar, Ehsan Salarkia   +6 more
doaj  

Functionally redundant RXLR effectors from Phytophthora infestans act at different steps to suppress early flg22-triggered immunity.

PLoS Pathogens, 2014
Genome sequences of several economically important phytopathogenic oomycetes have revealed the presence of large families of so-called RXLR effectors.
Xiangzi Zheng, Hazel McLellan, Malou Fraiture, Xiaoyu Liu, Petra C Boevink, Eleanor M Gilroy, Ying Chen, Kabindra Kandel, Guido Sessa, Paul R J Birch, Frédéric Brunner   +10 more
doaj   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

Integrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu, Ruiping Xu, Baofa Yin, Ruiyong Wu, Youheng Wei, Dehua Wang, Wanhong Wei   +6 more
wiley   +1 more source

Dynamin-Related Proteins Enhance Tomato Immunity by Mediating Pattern Recognition Receptor Trafficking

Membranes, 2022
Pattern recognition receptor (PRR) trafficking to the plasma membrane and endocytosis plays a crucial role in pattern triggered immunity (PTI). Dynamin-related proteins (DRPs) participate in endocytosis and recycling.
Meirav Leibman-Markus, Silvia Schuster, Beatriz Vasquez-Soto, Maya Bar, Adi Avni, Lorena Pizarro   +5 more
doaj   +1 more source

Crosstalk between Calcium and ROS Signaling during Flg22-Triggered Immune Response in Arabidopsis Leaves

Plants, 2021
Calcium and reactive oxygen species (ROS) are two of the earliest second messengers in response to environmental stresses in plants. The rise and sequestration of these messengers in the cytosol and apoplast are formed by various channels, transporters ...
Matthew J. Marcec, Kiwamu Tanaka
doaj   +1 more source

Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters

Andrology, EarlyView.
ABSTRACT Background Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on the effects of EVs on spermatozoa have focused on ejaculated spermatozoa, which have already been exposed to their own native
Ana Moya‐Fernández, Santa María Toledo‐Guardiola, Peter Silke, Sergio Navarro‐Serna, Carmen Matás   +4 more
wiley   +1 more source

Releasing hidden MAMPs from precursor proteins in plants

Trends in Plant Science
The recognition of pathogens by plants at the cell surface is crucial for activating plant immunity. Plants employ pattern recognition receptors (PRRs) to detect microbe-associated molecular patterns (MAMPs). However, our knowledge of the release of peptide MAMPs from their precursor proteins is very limited.
Changlong Chen, Renier A.L. van der Hoorn, Pierre Buscaill   +2 more
openaire   +3 more sources

Inappropriate Expression of an NLP Effector in Colletotrichum orbiculare Impairs Infection on Cucurbitaceae Cultivars via Plant Recognition of the C-Terminal Region

Molecular Plant-Microbe Interactions, 2018
The hemibiotrophic pathogen Colletotrichum orbiculare preferentially expresses a necrosis and ethylene-inducing peptide 1 (Nep1)-like protein named NLP1 during the switch to necrotrophy.
Nur Sabrina Ahmad Azmi, Suthitar Singkaravanit-Ogawa, Kyoko Ikeda, Saeko Kitakura, Yoshihiro Inoue, Yoshihiro Narusaka, Ken Shirasu, Masanori Kaido, Kazuyuki Mise, Yoshitaka Takano   +9 more
doaj   +1 more source

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source