Modulation of signaling pathways by DJ-1: An updated overview [PDF]
Redox Biology, 2022 Efforts have been made to understand the physiological and pathological role of DJ-1, a Parkinson’s disease (PD)-associated protein, to provide new insights into PD pathophysiology.
Margarida Neves +3 more
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An Exploration of Novel Bioactives from the Venomous Marine Annelid Glycera alba [PDF]
Toxins, 2023 The immense biodiversity of marine invertebrates makes them high-value targets for the prospecting of novel bioactives. The present study investigated proteinaceous toxins secreted by the skin and proboscis of Glycera alba (Annelida: Polychaeta), whose ...
Sónia Campos +6 more
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Modelo de manadas y aprendizaje social [PDF]
Revista de Economía Institucional, 2005 Para los economistas es importante saber cómo toman decisiones los individuos. Los agentes económicos suelen imitar las acciones de otros agentes. Cabe entonces preguntar por qué los individuos racionales imitan el comportamiento de otros y deciden no ...
Juan P. Herrera, Francisco Lozano Gerena
doaj +4 more sources
Comparative Analysis of Bursaphelenchus xylophilus Secretome Under Pinus pinaster and P. pinea Stimuli [PDF]
Frontiers in Plant Science, 2021 The pinewood nematode (PWN), Bursaphelenchus xylophilus, the pine wilt disease’s (PWD) causal agent, is a migratory endoparasitic nematode skilled to feed on pine tissues and on fungi that colonize the trees. In order to study B.
Hugo Silva +5 more
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Virulence Biomarkers of Bursaphelenchus xylophilus: A Proteomic Approach [PDF]
Frontiers in Plant Science, 2022 The pinewood nematode (PWN), Bursaphelenchus xylophilus, one of the most serious forest pests worldwide, is considered the causal agent of the pine wilt disease (PWD). The main host species belong to the genus Pinus, and a variation in the susceptibility
Joana M. S. Cardoso +6 more
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Proteome dataset of sea bass (Dicentrarchus labrax) skin-scales exposed to fluoxetine and estradiol [PDF]
Data in Brief, 2022 Contamination of aquatic ecosystems with anthropogenic pollutants, including pharmaceutical drugs, is a major concern worldwide. Aquatic organisms such as fish are particularly at risk of exposure to pollutants.
Liliana Anjos +7 more
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Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway [PDF]
Frontiers in Pharmacology, 2022 Glioblastoma (GB) is the most malignant and frequent primary tumor of the central nervous system. The lack of diagnostic tools and the poor prognosis associated with this tumor type leads to restricted and limited options of treatment, namely surgical ...
Mariana Magalhães +18 more
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Chronic treatment with D2-antagonist haloperidol leads to inhibitory/excitatory imbalance in striatal D1-neurons [PDF]
Translational Psychiatry, 2023 Striatal dysfunction has been implicated in the pathophysiology of schizophrenia, a disorder characterized by positive symptoms such as hallucinations and delusions. Haloperidol is a typical antipsychotic medication used in the treatment of schizophrenia
Cátia Santa +10 more
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Spotted Fever Group Rickettsia Trigger Species-Specific Alterations in Macrophage Proteome Signatures with Different Impacts in Host Innate Inflammatory Responses [PDF]
Microbiology Spectrum, 2021 The molecular details underlying differences in pathogenicity between Rickettsia species remain to be fully understood. Evidence points to macrophage permissiveness as a key mechanism in rickettsial virulence.
Pedro Curto +4 more
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Defective mitochondria‐lysosomal axis enhances the release of extracellular vesicles containing mitochondrial DNA and proteins in Huntington's disease [PDF]
Journal of Extracellular Biology, 2022 Mitochondrial and autophagy dysfunction are mechanisms proposed to be involved in the pathogenesis of several neurodegenerative diseases. Huntington's disease (HD) is a progressive neurodegenerative disorder associated with mutant Huntingtin‐induced ...
Margarida Beatriz +6 more
doaj +2 more sources