Results 41 to 50 of about 9,370 (287)

Relationship between Women`s Body Dissatisfaction, Sense of Coherence and Physical Activity

Baltic Journal of Sport and Health Sciences, 2018
Background. Socio-cultural pressure exerted by the environment and the media makes the majority of women take care of their bodies. That is especially true in Western culture which promotes slimmer women in recent decades. Methods.
Audronė Dumčienė, Jolanta Gedvilienė, Vaidas Mickevičius   +2 more
doaj   +1 more source

Manageability of complex organisational systems – system-theoretical confines of control

Organization, Technology and Management in Construction: An International Journal, 2022
The task of organisation is based on breaking up complex systems into a number of less complex subsystems where the interfaces are well-determined leading inevitably to hierarchical structures.
Eber Wolfgang
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Manageability and controllability of project risk : theoretical concepts and managerial perspectives [PDF]

, 2016
This study explores the concepts of manageability and controllability of project risk, from academic and managerial perspectives. It aims to understand the managerial perception of these concepts, distinguish the differences between them from academic ...
Arini, Hilya Mudrika
core   +2 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Toward quantifying system manageability [PDF]

, 2008
Manageability directly influences a system’s reliabil-ity, availability, security, and safety, thus being a key in-gredient of system dependability. Alas, we do not have today a good way to measure manageability or reason quantitatively about it, and ...
George Candea, Candea, George
core  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Cognitive functions and sense of coherence in patients with carotid artery stenosis—Preliminary report

Frontiers in Psychiatry, 2023
BackgroundThere is scarcely any data in the available literature on the relationship between sense of coherence (SOC) and cognitive functioning, and no information on the relationship between SOC and cognitive parameters in patients with carotid ...
Magdalena Piegza, Paweł Dębski, Kamil Bujak, Izabela Jaworska, Piotr Gorczyca, Robert Pudlo, Maciej Żerdziński, Maciej Żerdziński, Jacek Piegza   +8 more
doaj   +1 more source