Results 51 to 60 of about 119,978 (262)

The Financial Implications of Coverage of Smoking Cessation Treatment by Managed Care Organizations

open access: yesInquiry: The Journal of Health Care Organization, Provision, and Financing, 2004
This paper presents results from a simulation of the financial impact and cost effectiveness of smoking cessation in a hypothetical managed care organization (MCO), using data from three large managed care organizations and from existing literature. With
Kenneth E. Warner   +2 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Consumer-directed services: lessons and implications for integrated systems of care

open access: yesInternational Journal of Integrated Care, 2003
Over the past decade, policy makers in developed countries have begun to pay increasing attention to reform of the long-term care system for the frail elderly and younger people with disabilities.
Dennis L. Kodner
doaj   +3 more sources

Disease management projects and the Chronic Care Model in action: baseline qualitative research

open access: yesBMC Health Services Research, 2012
Background Disease management programs, especially those based on the Chronic Care Model (CCM), are increasingly common in the Netherlands. While disease management programs have been well-researched quantitatively and economically, less qualitative ...
Walters Bethany   +3 more
doaj   +1 more source

Analysis of Tuberculosis Program Management in Primary Health Care

open access: yesInfectious Disease Reports, 2020
Background: This study discusses the analysis of Tuberculosis (TB) program management at the Perak Timur Primary Health Care (PHC) and the Sawahan PHC in Surabaya. Early detection and adequate treatment can prevent transmission and improve control programs. Objective: This study aims to analyze management of the tuberculosis program at PHCs in Surabaya.
Ni Njoman Juliasih   +2 more
openaire   +4 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Managed Care After Discharge of COVID-19 Patients in North Iran [PDF]

open access: yesعلوم بهداشتی ایران
Background and Purpose: After-discharge follow-up is one of the branches of managed care used for information exchange, health education, early diagnosis of symptoms, symptom management, and high-quality aftercare services.
Roya Malekzadeh, Touraj Assadi
doaj  

THE ROLE OF A PARTICIPATORY SPACE IN THE DEVELOPMENT OF CITIZENSHIP

open access: yesJournal of Social Intervention, 2019
Research and policymaking are paying increasing attention to the development of citizenship, stimulated by the transition towards a participatory society.
Max Axel Huber   +5 more
doaj   +1 more source

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