Results 101 to 110 of about 20,758,202 (342)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
IWMI Strategic plan 2009-2013: water for a food-secure world [PDF]
Strategy planning / Research institutes / Institutional development / Research priorities / Water resource management / Water ...
International Water Management Institute (IWMI).
core
Contact Information for the Members of the Commission on the Future of Worker-Management Relations [PDF]
, 1994 Contact_Info_Dunlop_Commission.pdf: 154 downloads, before Oct.
Commission on the Future of Worker-Management Relations
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Assessment of environmental flows for river health [PDF]
, 2019 International Water Management Institute
core +1 more source
The food and water crisis [PDF]
Food production, Food supply, Urban agriculture, Water ...
International Water Management Institute (IWMI).
core
State-of-the-art approaches for evidence-based springshed management to increase resilience to climate change in Nepal [PDF]
, 2019 • A thorough understanding of spring systems is essential to design evidence-based springshed interventions. The necessary information can be collected by conducting hydrometeorological monitoring, hydrogeological assessments and isotope analysis ...
International Water Management Institute
core
Automated extraction of ejection fraction for quality measurement using regular expressions in Unstructured Information Management Architecture (UIMA) for heart failure [PDF]
, 2012 Jennifer H. Garvin +11 more
openalex +1 more source