Results 101 to 110 of about 5,218,208 (307)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Enhancing strategic flexibility for sustainable agro-industrial enterprises in transition economies: a fuzzy multicriteria approach

Technological and Economic Development of Economy
The article demonstrates that managing an enterprise’s strategic flexibility effectively is key to its competitiveness and market sustainability. The authors have developed a comprehensive model of strategic flexibility management of an agro-industrial ...
Maksym W. Sitnicki, Natalia Wasilewska, Valeriy Balan, Inna Tymchenko, Mirosław Wasilewski, Olena Pimenowa, Svetlana Sitnicka   +6 more
doaj   +1 more source

Associations Between Social Vulnerability and Providing Evidence-Based Diabetes Prevention and Management Activities in South Carolina, 2019. [PDF]

Prev Chronic Dis, 2023
Mandelbaum J, Brightharp C, Myers K, Hicks S.   +3 more
europepmc   +1 more source

Hikester - the event management application

, 2018
Today social networks and services are one of the most important part of our everyday life. Most of the daily activities, such as communicating with friends, reading news or dating is usually done using social networks.
Khatipov, Rinat, Mazzara, Manuel, Negimatzhanov, Aydar, Rivera, Victor, Zakirov, Anvar, Zamaleev, Ilgiz   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington’s disease

Journal of Biomedical Science
Background Huntington’s disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting mainly the striatum and the cortex.
Tamara Vasilkovska, Somaie Salajeghe, Verdi Vanreusel, Johan Van Audekerke, Marlies Verschuuren, Lydiane Hirschler, Jan Warnking, Isabel Pintelon, Dorian Pustina, Roger Cachope, Ladislav Mrzljak, Ignacio Muñoz-Sanjuan, Emmanuel L. Barbier, Winnok H. De Vos, Annemie Van der Linden, Marleen Verhoye   +15 more
doaj   +1 more source

Attracting the Tourism Potential of Ukraine to the “Unloading” of the World Flows [PDF]

Problemi Ekonomiki, 2018
The article highlights the study of ways and possibilities for attracting the domestic tourism potential in accepting part of the growing world tourist flow to solve the problem of the “overloading” of famous cultural monuments and wonders of the world ...
Raкhman Mahbubur S.
doaj  

The impact of internal and external green supply chain management activities on performance improvement: evidence from the automobile industry. [PDF]

Heliyon, 2022
Li X, Liu D, Zhang Z, Cheng T, Liu L, Yuan J.   +5 more
europepmc   +1 more source

The Western Pacific Fishery Information Network: A Fisheries Information System [PDF]

, 1993
The Western Pacific Fishery Information Network (WPACFlN) is an intergovernmental agency cooperative program sponsored by the National Marine Fisheries Service (NMFS) to help participating island fisheries agencies carry out data collection, analysis ...
Hamm, David C.
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source