The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Corporate social responsibility and management control [PDF]
, 2011 ESSEC Working paper. Document de recherche de l'ESSEC / ISSN : 1291-9616 WP1114This paper focuses on the management control processes associated with Corporate Social Responsibility (CSR) issues management in organisations.
Mottis, Nicolas, Mersereau, Alexander
core +1 more source
Traditional budgeting during financial crisis
Management Letters/Cuadernos de Gestión, 2015 This study examines the evolution of budgeting practices in the extremely difficult Spanish economic environment. In order to analyse if companies are still maintaining their budgeting process and if, right now, they are facing more difficulties in ...
Marie Anne Lorain +2 more
doaj +1 more source
Implementation of hybrid optimized battery controller and advanced power management control strategy in a renewable energy integrated DC microgrid. [PDF]
PLoS One, 2023 Al Sumarmad K +3 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Administrative SciencesBackground: Digital transformation has emerged as an important theme in contemporary organisational studies, particularly within public sector institutions striving to enhance operational efficiency, improve service delivery, and foster innovation.
Fredrik Molin, Eva Norrman Brandt
doaj +1 more source
University Archives Autonomous Management Control System under the Internet of Things and Deep Learning Professional Certification. [PDF]
Comput Intell Neurosci, 2022 Ma Y, Dai B, Ding B.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Designing a Re-Usable Coordination Module for Cooperative Industrial Control Applications [PDF]
, 1996 Distributed artificial intelligence (DAI) systems, in which multiple agents communicate and co-operate with one another to achieve their individual and collective goals, are a promising enabling technology for constructing large, real world industrial ...
Pople, J. A. +5 more
core +1 more source
Type 2 Diabetes Management, Control and Outcomes During the COVID-19 Pandemic in Older US Veterans: an Observational Study. [PDF]
J Gen Intern Med, 2022 Aubert CE +5 more
europepmc +1 more source