Results 81 to 90 of about 5,251,558 (335)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A New Path for Management Education in an Emerging Country
Management education has a long history in Turkey, but it still has so many structural problems. Both scholars and practitioners complain about the inconsistencies with theoretical and practical sides of university education in management field.
Ayşe Çoban Kayacı
doaj +1 more source
Rural Management Education in India: A Retrospect [PDF]
The paper reviews the state of rural management education in India. Using the setting up of the Institute of Rural Management Anand [IRMA] as a pivot, the paper examines the difficulties in establishing specialized management schools, the design of the ...
Sriram M S
core
Development and construction of China [PDF]
Libraries in China's higher education institutions have been developing in keeping pace with the flourishing development of China's higher education.
DAI Longji +6 more
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The Middle Eastern Biodiversity Network: Generating and sharing knowledge for ecosystem management and conservation [PDF]
Despite prevailing arid conditions, the diversity of terrestrial and freshwater biota in the Middle East is amazingly high and marine biodiversity is among the highest on Earth.
Al-Jumaily, Masaa +5 more
core +2 more sources
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Results Based Risk Management Education [PDF]
Risk and Uncertainty, Teaching/Communication/Extension/Profession,
Fiess, Dennis, Newkirk, Jon
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Consultancy in management education [PDF]
The chapter interrogates the teaching and application of management consultancy as part of an MBA and examines its relevance in management education. Mature and experienced students, many with impressive CVs recording multiple career successes, demand that the core experience of their MBA programmes provide opportunities to apply theoretical knowledge ...
Matthias, Olga, Campbell, J.
openaire +2 more sources
Re-conceiving management education: Artful teaching and learning [PDF]
Artists derive inspiration from daily life. According to John Dewey, common experiences are transformed into works of art through a process of compression and expression.
Bathurst, Ralph +2 more
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