Results 91 to 100 of about 11,883,084 (368)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Special issue: Advances in Engineering Networks

open access: yesInternational Journal of Production Management and Engineering, 2019
This special issue of the International Journal of Production Management and Engineering is dedicated on the most recent and relevant research, theories and practices in Industrial Engineering and Operations Management presented at the 12th International
R. de Castro   +6 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Design of Examination Management System for Engineering Management

open access: yesIOP Conference Series: Earth and Environmental Science, 2020
Abstract Through the analysis of the engineering management training system, we know that the courses in the system can be divided into theoretical, practical and experimental courses. We aims to develop an examination management system by restructuring the evaluation process of the three types of courses.
Hualong Cai, Yong Yao, Jingwen Cai
openaire   +2 more sources

ENGLISH LANGUAGE LEARNING STRATEGIES: AN EXPLORATORY STUDY OF MANAGEMENT AND ENGINEERING STUDENTS

open access: yesJournal of English Education, 2018
Learning English as a foreign language, especially in a formal context, leads the students to have their own strategy in order to achieve the objective of learning. The strategy is considered as a helpful way to learn English better.
Berlinda Mandasari, L. Oktaviani
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Valuing Knowledge Management Impact on Engineering Design Activities [PDF]

open access: yes
Knowledge Management Systems (KMS) have been developed in Engineering Designactivities in order to improve the productivity of these activities. Nevertheless it is still verydifficult to identify the impact of such Systems on the Engineering Design ...
Aurélie Dudezert, Mickaël Gardoni
core  

RESEARCH ON MANAGEMENT AND APPLICATION OF TUNNEL ENGINEERING BASED ON BIM TECHNOLOGY

open access: yesJournal of Civil Engineering and Management, 2019
The emergence of BIM technology has provided powerful technical means for realizing informatization and digitization in the field of engineering construction, which remarkably promotes the transformation and advance of production and management modes in ...
Z. Song   +5 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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