Results 71 to 80 of about 13,333,808 (308)

Investigation of pavement cracking on SR-4 and demonstration of the multi-head breaker in fracturing reinforced concrete pavements before asphalt overlay [PDF]

, 2006
"May 2006."; Includes bibliographical references (p. 63-65).; Final report.; Prepared by Infrastructure Management and Engineering Inc., sponsored by the Ohio Dept.
Rajagopal, Arudi., Infrastructure Management and Engineering Inc.   +1 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Transition to IS project de-escalation: An exploration into management executive's influence tactics [PDF]

, 2011
10.1109/TEM.2010.2048908IEEE Transactions on Engineering Management581109 ...
PAN, Shan Ling, Pan, G., PAN, Gary, Pan, S.L.   +3 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

International Conference on Industry, Engineering, and Management Systems 2017

, 2017
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'17 conference committee: Nael Aly (Conference Co-Chair); Ahmad Elshennawy (Conference Co-Chair); Gamal Waheba (Program Chair ...
International Conference on Industry, Engineering, and Management Systems
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

JMEI

Published in SOAR: Shocker Open Access Repository by the Wichita State University Libraries Technical Services, October 2024.Copyright of the Journal of Management and Engineering Integration is the property of the Association of Industry, Engineering ...
Association for Industry, Engineering and Management Systems (AIEMS)
core   +1 more source

International Conference on Industry, Engineering, and Management Systems 2019

, 2019
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'19 conference committee: Gamal Weheba (Conference Chair); Hesham Mahgoub (Conference Co-Chair); Sandra Furterer (Program Chair);
International Conference on Industry, Engineering, and Management Systems
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source