Results 71 to 80 of about 3,190,588 (297)
Valuing Knowledge Management Impact on Engineering Design Activities [PDF]
Knowledge Management Systems (KMS) have been developed in Engineering Designactivities in order to improve the productivity of these activities. Nevertheless it is still verydifficult to identify the impact of such Systems on the Engineering Design ...
Aurélie Dudezert, Mickaël Gardoni
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Proceedings of the Canadian Engineering Education Association (CEEA), 2011 This paper reports on the findings of a combined qualitative and quantitative research case study into engineering management (EM) practices in offshore Oil and Gas industry in St. John's, Newfoundland. It was designed to examine the management challenges faced by EMs in this sector, how EMs are selected, how engineers respond to being made managers ...
Paul Ryan, Leonard Lye, Amy Hsiao
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu[Objective] The traditional management process for engineering vehicle night-time operations faces challenges such as poor coordination, unclear station clearance status, and limited number of on-line engineering vehicle operations, which significantly ...
DONG Yiyi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Applying COCOMO II for a DO-178C Safety-Critical Software Effort Estimation
Journal of Aerospace Technology and Management, 2019 This paper provides a real example of applying COCOMO II as an estimation technique for the required software development effort in a safety-critical software application project following the DO-178C processes. The main goal and contribution of the case
Lucas Pereira dos Santos +1 more
doaj +3 more sources
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Highly improved light harvesting and photovoltaic performance in CdTe solar cell with functional designed 1D-photonic crystal via light management engineering. [PDF]
Sci Rep, 2022 Çetinkaya Ç +6 more
europepmc +1 more source
Management issues in systems engineering [PDF]
When applied to a system, the doctrine of successive refinement is a divide-and-conquer strategy. Complex systems are sucessively divided into pieces that are less complex, until they are simple enough to be conquered.
Aster, Robert +7 more
core +1 more source