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Management Engineering: A New Perspective on the Integration of Engineering and Management Knowledge
, 2020 Engineering management has been historically focused on integrating scientific, engineering, and management know-how to contribute effectively to the functioning of organizations and industries.
Elia, Gianluca +2 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Recensione I IEEE Transactions on Engineering Management
, 2013 Recensione I IEEE Transactions on Engineering ...
THOMA, Grid
core +1 more source
Engineering, Project, and Production Management: Lessons [PDF]
Journal of Engineering, Project, and Production Management, 2013 This Journal always faces the challenge of bringing together the three disciplines in a common pool of management research. This edition provides at least a paper in each of the disciplines.
Kassim Gidado
doaj
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
SYSTEMATIC APPROACH OF THE PRODUCT LIFECYCLE COMPONENTS [PDF]
Annals: Series on engineering sciences (Academy of Romanian Scientists), 2013 Today, companies across numerous industries find themselves on the cusp of a product development revolution. The incorporation of software and electronics into mechanical-based products is driving a wave of new innovation as products become more like ...
Constantin Adrian ALEXE
doaj
International Conference on Industry, Engineering, and Management Systems (2013 : Cocoa Beach, Fla.)
, 2013 Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'13 conference committee: The Association for Industry, Engineering, & Management Systems (Sponsor); Nael Aly (Conference Co ...
International Conference on Industry, Engineering, and Management Systems
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International Conference on Industry, Engineering, and Management Systems 2020
, 2020 Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'20 conference committee: Wichita State University, College of Engineering (Sponsor); Gamal Weheba (Conference Chair); Hesham ...
International Conference on Industry, Engineering, and Management Systems
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source