Results 101 to 110 of about 3,159,903 (327)
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Engineering change management challenges and management cybernetics
Competitive advantage in mature industries is very important for companies to thrive in the market. One possibility for attaining competitive advantage is pursuing systematic product development (PD) efforts, which keep the requirements of the customers in focus.
F. Elezi, T. G. Maier, U. Lindemann
openaire +2 more sources
Engineering Approaches for Programming Agent-Based IoT Objects Using the Resource Management Architecture [PDF]
Fabian César Pereira Brandão Manoel +4 more
openalex +1 more source
Designing Enterprise Resources Planning Application for Integrating Main Activities in a Simulator Model of SCM Network Distribution [PDF]
Collaborative supply chain is a specific topic in supply chain management and studied by industrial engineering students in supply chain management course.
Hakim, Inaki Maulida +3 more
core
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Town of New Durham Stormwater Management & Erosion Control Project [PDF]
Appledore Engineering worked with the New Durham Planning Board to develop a stormwater management and erosion control ordinance and to adopt complimentary improvements to the town’s site plan review and subdivision ...
Town of Durham
core +2 more sources
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Prototype of a new Engineering Masters project model: Working with marketing and software faculties to commercially kickstart university research [PDF]
We describe a Master of Engineering (500-level) project modelled on the real-world arrangement where engineers work with marketing and software groups to prepare a product for commercialisation.
Barr-Smith, Anthony +7 more
core +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source

