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In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Creativity in Mass-Education Contexts [PDF]
This paper discusses a learning framework (working title: ‘fog framework’) that has been developed in response to the challenge of teaching creative subjects in a mass-education context.
Anusas, M.
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Artificial intelligence in prognostics and health management of engineering systems
Sunday Ochella+2 more
semanticscholar +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
Statistical Tables for Science, Engineering, Management and Business Studies [PDF]
J. E. J., John H. Murdoch, Susan Baines
openalex +3 more sources
Necessity of Management Course for Chemical Engineering
Chemical engineering is one of the most versatile and largest engineering fields. Chemical engineering graduates have different status based on their area of study and responsibility in society.
Mohsen Pirdashti+2 more
doaj +1 more source
Discussion: “The Engineering Method in Management” (Peterson, Andrew I., 1940, Trans. ASME, 62, pp. 587–590) [PDF]
Paul T. Norton
openalex +1 more source
Methodical Problems in Organic Farming Research [PDF]
Workshop presentation with particular focus on values, transferability and praxis relevance of organic farming research. Examples from agricultural engineering lead to the conclusion, that prototype farming, goal oriented project management ...
Schäfer, Winfried
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