Results 31 to 40 of about 585,922 (260)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A conceptual management model for the creation of an innovate engineering product
Ученые записки Российской академии предпринимательстваThe purpose of the research is to develop a conceptual model of innovation management in the creation of an innovative engineering product. Research object: innovative engineering.
I. S. Mukhin
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2022 With the advent of the big data era, information technology and intelligent algorithms are more and more widely used. In the engineering project management industry, big data technology and dynamic modeling have achieved good results.
Xiaowen Zhuang, Chuanbao Wu
doaj +1 more source
Managing engineers effectively
IEEE Transactions on Engineering Management, 1983 The professional needs of engineering personnel are investigated. Their degree of satisfaction is positively associated with overall engineering performance. All of the sixteen specific needs analyzed involve three primary issues: (1) people skills, (2) organizational structure, and (3) management style, influenced by the task to be performed and the ...
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of Asian Architecture and Building EngineeringIn the era of intelligent construction, engineering management requires diverse abilities that cannot be provided through traditional engineering management education.
Dingli Liu +4 more
doaj +1 more source
Construction and Application of Digital Asset Platform for Hydropower Engineering
Renmin Zhujiang, 2022 The development of informatization and digitization of hydropower engineering is exposed to problems such as inconsistent data standards,uneven data quality,scattered data storage,weak correlation between data,and difficult data sharing.By referring to ...
JIA Yuhao
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source