Results 41 to 50 of about 14,026,647 (263)

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Construction and Application of Digital Asset Platform for Hydropower Engineering

open access: yesRenmin Zhujiang, 2022
The development of informatization and digitization of hydropower engineering is exposed to problems such as inconsistent data standards,uneven data quality,scattered data storage,weak correlation between data,and difficult data sharing.By referring to ...
JIA Yuhao
doaj  

Discrete Dynamic Modeling Analysis of Engineering Management and Quality Optimization Innovation Mode Based on Big Data Intelligent Algorithm

open access: yesDiscrete Dynamics in Nature and Society, 2022
With the advent of the big data era, information technology and intelligent algorithms are more and more widely used. In the engineering project management industry, big data technology and dynamic modeling have achieved good results.
Xiaowen Zhuang, Chuanbao Wu
doaj   +1 more source

Journal of Management & Engineering Integration, v.12 no.2 (Winter)

open access: yes, 2019
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, November 2022.Evaluating the impact of student constructed four-bar mechanisms on achieving learning objectives in an Industrial Mechanisms course
Association for Industry, Engineering and Management Systems (AIEMS)
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A conceptual management model for the creation of an innovate engineering product

open access: yesУченые записки Российской академии предпринимательства
The purpose of the research is to develop a conceptual model of innovation management in the creation of an innovative engineering product. Research object: innovative engineering.
I. S. Mukhin
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Sustainable performance management using resilience engineering

open access: yesInternational Journal of Engineering Business Management, 2020
Several efforts have focused on the continuous improvement of firm performance, but many disturbances still occur because of various random failures. Resilience which is the ability to withstand shock and maintain critical function, has been recognized ...
Hafida Bouloiz
doaj   +1 more source

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