Results 111 to 120 of about 9,892,911 (373)

Information logistics: A production-line approach to information services [PDF]

Logistics can be defined as the process of strategically managing the acquisition, movement, and storage of materials, parts, and finished inventory (and the related information flow) through the organization and its marketing channels in a cost ...
Adams, Dennis, Lee, Chee-Seng
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Correction to: Severity: a QoS-aware approach to cloud application elasticity

Journal of Cloud Computing: Advances, Systems and Applications, 2021
Andreas Tsagkaropoulos, Yiannis Verginadis, Nikos Papageorgiou, Fotis Paraskevopoulos, Dimitris Apostolou, Gregoris Mentzas   +5 more
doaj   +1 more source

Perceptions of Physicians Regarding Implementation of Hospital Management Information Systems in a Tertiary Setting Hospital of a Developing Country. [PDF]

Cureus, 2021
Hussain R, Ali W, Sohaib M.
europepmc   +1 more source

Optimization Alternatives of Information Systems for Risk Management [PDF]

The focus of this article lies on synthesizing the requirements a risk management information system should meet in order to ensure an efficient risk management within a company, but also on presenting the architecture of the information system proposed ...
Iulia APOSTOL-MAURER
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Gamified Massive Open Online Course to Enhance Learner Engagement and Learning Outcomes

Jurnal Teknologi Pendidikan
The use of Ruangguru app significantly increases learner engagement in the learning process. Ruangguru app uses gamification method in its learning design.
Rikky Ihza Pratama, Astari Retnowardhani
doaj  

Integrated Financial Management Information Systems: Guidelines for effective implementation by the public sector of South Africa

South African Journal of Information Management, 2012
Background: Integrated Financial Management Information Systems (IFMIS) can improve public sector management by providing real-time financial information to managers in order to enhance their decision-making capabilities.
Christoffel J. Hendriks
doaj  

An explainable artificial intelligence feature selection framework for transparent, trustworthy, and cost-efficient energy forecasting

Energy and AI
Accurate forecasting of renewable power generation is crucial for grid stability and cost efficiency. Feature selection in AI-based forecasting remains challenging due to high data acquisition cost, lack of transparency, and limited user control.
Leonard Kost, Sarah K. Lier, Michael H. Breitner   +2 more
doaj   +1 more source