Results 141 to 150 of about 9,892,911 (373)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Management accountants and strategic management accounting: The role of organizational culture and information systems

Management Accounting Research, 2021
Wael Hadid, Mahmoud Al-Sayed
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Critical Success Factors Influencing the Behavioral Intention to Adopt Smart Home Technologies

IEEE Access
Drawing from established models of technology acceptance, this study presents a comprehensive model that explores the influence of both Innovation-related factors and Citizen-related factors. Furthermore, it examines how trust in Internet of Things (IoT)
Nour Qatawneh, Ali Aljaafreh, O'la Hmoud Al-Laymoun, Raid Aladaileh   +3 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The Acceptance of Health Information Systems by Senior Citizens: A Technology Acceptance Model

Экономика: стратегия и практика
With the accelerating ageing of the population, there is an increasing need for older citizens to adapt to using digital healthcare solutions, including Health Information Systems (hereinafter – HIS), as an important element of affordable medicine.
Ş. Yahşi, I. T. Medeni, T. D. Medeni, M. S. Güzel   +3 more
doaj   +1 more source

INFORMATION TECHNOLOGY OR INFORMATION SYSTEM: SOLUTION FOR EFFECTIVE BUSINESS COMMUNICATION IN OPERATION, MANAGEMENT AND DECISION MAKING. [PDF]

, 2019
u h, Hunton James E, a a, Iswandry Elkana Immanuel. S, a a, a, i s, a   +7 more
openalex   +1 more source

A database management capability for Ada [PDF]

The data requirements of mission critical defense systems have been increasing dramatically. Command and control, intelligence, logistics, and even weapons systems are being required to integrate, process, and share ever increasing volumes of information.
Chan, Arvola, Danberg, SY, Fox, Stephen, Landers, Terry, Nori, Anil, Smith, John M.   +5 more
core   +1 more source

Modeling cloud resources using machine learning [PDF]

, 2013
Cloud computing is a new Internet infrastructure paradigm where management optimization has become a challenge to be solved, as all current management systems are human-driven or ad-hoc automatic systems that must be tuned manually by experts. Management
Berral, Josep Ll., Gavaldà Mestre, Ricard, Torres Viñals, Jordi   +2 more
core   +1 more source