Results 51 to 60 of about 1,270,490 (317)

Issues in public information systems development: The impact of regionalised organisational structure [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThis thesis highlights the critical impact the effects of regionalised organisational structure and external political pressures have on the development of ...
Folkerd, Christopher
core  

Managing Emerging Infectious Diseases with Information Systems: Reconceptualizing Outbreak Management through the Lens of Loose Coupling

open access: yes, 2012
Increasing global connectivity makes emerging infectious diseases (EID) more threatening than ever before. Various information systems (IS) projects have been undertaken to enhance public health capacity for detecting EID in a timely manner and ...
Chen, Yi-Da; Brown, Susan A.; Hu, Paul Jen-Hwa; King, Chwan-Chuen; Chen, Hsinchun   +1 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Antecedents of Gacha gaming intention: Extending UTAUT2 with structural video game characteristics

open access: yesComputers in Human Behavior Reports
Mobile gacha games, featuring chance-based virtual item collections and lottery-like mechanics, have become immensely popular among global youth. Therefore, many game developers are developing new gacha games or implementing gacha mechanics into existing
Adidharma Ekaputra Kesuma   +1 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Management Information Systems Research Center (MISRC) Accomplishment Summary (1971-74)

open access: yes, 1974
Management Information Systems Research Center. (1974). Management Information Systems Research Center (MISRC) Accomplishment Summary (1971-74).
Management Information Systems Research Center
core  

DESI Integration and Enterprise Productivity in the EU: A Business Model Innovation Perspective on Digital Transformation

open access: yesSystems
Digital transformation reshapes firms into more digital, data-driven, and customer-centric organizations. Because it often supports innovation, firms are widely expected to benefit from higher performance and productivity.
Ofelia Ema Aleca, Florin Mihai
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Strategic management plan for geographic information systems technology Geographic information systems technology

open access: yes, 1990
"September 1990."Section 1: Executive Summary -- Section 2: Organization of the Plan -- Section 3: Strategic Planning Policy -- Section 4: Goals of the GIS Technology Management Plan -- Section 5: Background -- Section 6: The Potential of GIS Technology ...
Kansas Geographic Information Systems Policy Board
core  

Information systems management maturity and information technology security effectiveness [PDF]

open access: yes, 2004
vii, 129 leaves ; 29 cm.Modern societies rely on Information Systems (IS), yet their protection has long been considered ineffective. Researchers and practitioners have struggled to understand the persistence of this phenomenon, but both agree that IS ...
Spicer, Garry   +1 more
core  

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