Results 61 to 70 of about 5,063,922 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Co-evolution of Information Systems in Fast-Growing Small Firms [PDF]

open access: yes, 2003
The paper examines the co-evolution of different dimensions of information systems for a sample of fast-growing small firms. The investigation uses primary source longitudinal empirical evidence.
Reid, Gavin C., Smith, Julia A.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Algoritmo de aprendizagem profunda compreensiva para compreender o papel das redes sociais na percepção do consumidor em relação ao consumo sustentável

open access: yesRAE: Revista de Administração de Empresas
Esta pesquisa propõe um algoritmo abrangente de aprendizado profundo para compreender o papel das redes sociais na percepção do consumidor em relação ao consumo sustentável.
Ceren Cubukcu Cerasi   +3 more
doaj   +1 more source

Constraints in binary semantical networks [PDF]

open access: yes
Information Systems;Management Information Systems;Networks;management information ...
Nienhuys-Cheng, S.-H.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hızlı Tüketim Mallarına Yönelik Tüketici Yorumlarında Odak Sorunu: Ürün mü, Satış Hizmeti mi Değerlendiriliyor?

open access: yesOnline Academic Journal of Information Technology, 2018
Bu çalışmanın amacı, hızlı tüketim malları gibi spesifik ürün gruplarına yönelik yorumların ürüne mi, ürünün satışı için sunulan hizmete mi yönelik olduğu sorusuna yanıt aramaktır.
Adem Akbıyık, Ece Nur Çakar
doaj   +1 more source

Aligning enterprise risk management with business strategy and information systems [PDF]

open access: yes, 2011
Business leaders recognise effective risk management as one of the main success drivers for enterprises. Even though the Enterprise Risk Management (ERM) concept has evolved significantly in the past years, in the aftermath of recent economic crises it ...
Althonayan, A, Keith, J, Misiura, A
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Sine Cosine Optimization With Deep Learning–Driven Object Detector for Visually Impaired Persons

open access: yesJournal of Mathematics
In real-time, visually impaired persons face challenging issues in identifying and avoiding obstacles in their path, making it difficult to move around freely and confidently.
Hadeel Alsolai   +3 more
doaj   +1 more source

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