Results 81 to 90 of about 1,029,162 (268)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Ensemble-based high-performance deep learning models for medical image retrieval in breast cancer detection

open access: yesScientific Reports
As digital imaging in healthcare grows quickly, dealing with vast medical image data is getting trickier. Content-Based Medical Image Retrieval (CBMIR) systems help with this, but they struggle because of the gap between simple image details and what ...
Aya E. Fawzy   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Integrated Financial Management Information Systems: Guidelines for effective implementation by the public sector of South Africa

open access: yesSouth African Journal of Information Management, 2012
Background: Integrated Financial Management Information Systems (IFMIS) can improve public sector management by providing real-time financial information to managers in order to enhance their decision-making capabilities.
Christoffel J. Hendriks
doaj  

An explainable artificial intelligence feature selection framework for transparent, trustworthy, and cost-efficient energy forecasting

open access: yesEnergy and AI
Accurate forecasting of renewable power generation is crucial for grid stability and cost efficiency. Feature selection in AI-based forecasting remains challenging due to high data acquisition cost, lack of transparency, and limited user control.
Leonard Kost   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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