Results 101 to 110 of about 4,031,415 (300)

THE FIRST PLAN FOR WATER RESOURCES MANAGEMENT OF SOMEȘ-TISA CATCHMENT AREA [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2014
With time, after Romania’s accession to the E.U., the national legislation adhered to the Water Framework Directive. In the study we present the Someş and Tisa river catchments management and development plans, from the beginnings till today.
SOFRONIE C., STOICA F.
doaj  

A data management plan for the NESHIE observational study. [PDF]

open access: yesFront Genet, 2023
Strydom A, Van Rensburg J, Pepper MS.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Environmental and ecological architects: Guidelines for the Chilean temperate rainforest management derived from the monito del monte (Dromiciops gliroides) conservation Arquitectos ambientales y ecológicos: Pautas para la gestión ambiental del bosque templado lluvioso de Chile derivadas de la conservación del monito del monte (Dromiciops gliroides)

open access: yesRevista Chilena de Historia Natural, 2011
Land use change is one of the main biodiversity threats. Due to this change, natural habitats such as the South American temperate rainforests have been rapidly degraded, fragmented, and lost.
FRANCISCO E FONTÚRBEL, JAIME E JIMÉNEZ
doaj  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Management in a neotropical show cave: planning for invertebrates conservation

open access: yesInternational Journal of Speleology, 2012
Lapa Nova is a dolomitic cave about 4.5 km long located in northwestern Minas Gerais state, Brazil. The cave experiences intense tourism, concentrated over a single period of the year, during the Feast of Our Lady of Lapa.
Thais Giovannini Pellegrini   +1 more
doaj  

NHEP Year 11 Work Plan [PDF]

open access: yes, 2006
The New Hampshire Estuaries Project (NHEP) is part of the U.S. Environmental Protection Agency’s National Estuary Program which is a joint local/state/federal program established under the Clean Water Act with the goal of protecting and enhancing ...
Hunter, Jennifer
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

National stroke management plan in Uruguay: Challenges and opportunities. [PDF]

open access: yesFront Neurol, 2022
Amorín I   +8 more
europepmc   +1 more source

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