Results 61 to 70 of about 12,039,942 (350)
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Faculty of Management Science and Informatics
The Faculty of Management at the University of Žilina was established in July 1990 as a result of a decision by the Academic Senate. In 1993 a new branch Management and Information Systems was created and in 1996 the name of the Faculty changed to the ...
Vladimir Jamrich
doaj +1 more source
Institutional Context of Pest Management Science in the Global South. [PDF]
Wyckhuys KAG, Hadi BAR.
europepmc +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A relação entre a Ciência da Informação e a Ciência da Administração
Este artigo discorre sobre a saga interdisciplinar entre a Ciência da Informação e a Ciência da Administração. O principal escopo dessa trama se concentra na informação, cujos atributos e propriedades se mesclam entre as duas Ciências.
Cláudio Augusto Alves +1 more
doaj +1 more source
Virtual power plant for energy management: Science mapping approach. [PDF]
Zarate-Perez E +6 more
europepmc +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Centralization of agricultural scientific data management model based on life cycle theory
Governments, research institutions and scientists all over the world have attached great importance to the construction, management and sharing of agricultural science data resources.Relevant international organizations and agricultural science data ...
Fei GAO, Guomin ZHOU, Rui MAN
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source

