Results 71 to 80 of about 2,125,948 (312)
Connecting Science and Management for Virginia's Tidal Wetlands
, 2008 Rivers & Coast is a periodic publication of the Center for Coastal Resources Management, Virginia Institute of Marine Science. The goal of Rivers & Coast is to keep readers well informed of current scientific understanding behind key environmental issues
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Information Management Policy - King Abdullah University of Science and Technology
, 2011 Records, Information and Archies Management Policy of King Abdullah University of Science and TechnologyRecords, Information and Archives Management Policy of King Abdullah University of Science and ...
King Abdullah University of Science and Technology
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A relação entre a Ciência da Informação e a Ciência da Administração
TransinformaçãoEste artigo discorre sobre a saga interdisciplinar entre a Ciência da Informação e a Ciência da Administração. O principal escopo dessa trama se concentra na informação, cujos atributos e propriedades se mesclam entre as duas Ciências.
Cláudio Augusto Alves +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Metadata Creation, Transformation and Discovery for Social Science Data Management: The DAMES Project Infrastructure [PDF]
, 2009 This paper discusses the use of metadata, underpinned by DDI (Data Documentation Initiative), to support social science data management. Social science data management refers broadly to the discovery, preparation, and manipulation of social science data ...
Lambert, Paul +6 more
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Behavioral science and Islamic Management [PDF]
مطالعات مدیریت بهبود و تحول, 1996 What today is named Behavioral Sciences is not anything except a means for increasing efficiency and effectiveness. In other words, most behaviorists look at behavior as a means for achieving the organizational goals.
seyedaliakbar afjaei
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Sand Dune and Beaches in Virginia: Science and Management
, 2009 Rivers & Coast is a periodic publication of the Center for Coastal Resources Management, Virginia Institute of Marine Science. The goal of Rivers & Coast is to keep readers well informed of current scientific understanding behind key environmental issues
core +1 more source