Results 101 to 110 of about 3,448,451 (296)

ECONOMIC PROCESS OPTIMIZATION DEPLOYED BY COMPANIES WITH COMPLEX ACTIVITY PRODUCTION – TRADE – SERVICES USING INFORMATICS SYSTEMS WITH INTEGRATED DATA MINING TECHNIQUES [PDF]

open access: yes
There are many economic processes deployed by companies with a complex activity that can be optimized, among the most common being: supply, production/service, distribution, sales, suppliers/customers relationships, inventory management, human resources ...
ANDRONIE, Mihai
core  

Management of a taxi services company through use of GPS positioning and GPRS data transfer [PDF]

open access: yes, 2010
The article describes methods of management and use of the GPS systems in taxi companies through application of advanced information technologies, such as GPS positioning and GPRS data transfer.
Belcheva Dragneva, Nikolina
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Innovative Approach to Conceptual Design of Enterprise Risk Management Software

open access: yesApplied Sciences
The paper shows the integration of the theoretical and practical aspects of designing an ERM software tool. The basic idea of the designed ERM is conceived in the form of an algorithm using the integration of ISO 3100, the COSO framework, the risk matrix
Petar Stanojević   +5 more
doaj   +1 more source

MAXIMISING PROFITS FROM PASSENGER TRANSPORT SERVICE USING TRANSPORTATION MODEL ALGORITHM [PDF]

open access: yes, 2007
The diversity and complexity of the different types of passenger transportations in operation today invokes the need for an efficient transport service management system.
Enyi , P. E.
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

An integrated model for cash transfer system design problem [PDF]

open access: yes, 2013
This paper presents an integrated model that incorporates strategic, tactical, and operational decisions for a cash transfer management system of a bank.
Dasci, Abdullah   +4 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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