Results 91 to 100 of about 30,356,521 (318)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Risk management system in metallurgical production

open access: yesMetalurgija, 2021
The main aim of the paper is to characterize the proposed model of risk management system. Threats identification and risk assessment of the systemic character result in taking action directed on risk elimination, minimization or financing.
T. Karkoszka
doaj  

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

Power management as a system-level inhibitor of modularity in the mobile computer industry [PDF]

open access: yes, 2004
Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2004.Includes bibliographical references (p. 88-90).Since the mid-90s, the computer industry has been very modular with respect to both product architecture and ...
Weinstein, Samuel K. (Samuel Keith), 1974-
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A system engineering approach to improving vehicle NVH attribute management [PDF]

open access: yes, 2008
Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, 2008.Includes bibliographical references (p. 134-137).This research is comprised of a detailed study of attribute management processes at a North American ...
Sacka, Michelle Lorraine
core  

Technological aspects of smart dairy farm development

open access: yesАграрная наука Евро-Северо-Востока, 2019
The article introduces the concept of «smart» farm as a tool for decision making support and provides the requirements necessary for its functioning. The aim of the research is the development of the concept of “smart” farm using modern system approach ...
Yu. A. Tsoy, R. A. Baisheva
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Enhancing vehicle safety management in training deployments : an application of system dynamics [PDF]

open access: yes, 2008
Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, 2008.Includes bibliographical references (p. 180-186).Organization Sierra-Tango is employing a systematic and methodical safety framework to manage risks in all ...
Lim, Kelvin F. H. (Kelvin Fang Hui)
core  

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