Results 121 to 130 of about 30,356,521 (318)
Innovation and SustainabilityThe article examines the peculiarities of forming a cybersecurity management system for enterprises in wartime. The paper presents the theoretical and applied aspect of this issue.
A. Zaverbnyj
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Integrated automotive exhaust engineering : uncertainty management [PDF]
, 2006 Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, 2006.Includes bibliographical references (p. 104-108).The global automotive industry has entered a stagnating period. Automotive OEMs and their tier suppliers are
Fang, Xitian, 1963-, Wan, Deming, 1967-
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Knowledge management of system interfaces and interactions from product development processes [PDF]
, 2001 Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2001.Includes bibliographical references (p. 149).A system architecture was developed and analyzed for a basic elevator system using a limited number of system ...
Thebeau, Ronnie E. (Ronnie Emile), 1970-
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Application of a systems-theoretic safety modeling technique for complex system mishap etiology
, 2003 Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2003.Includes bibliographical references (p.
Stealey, John, 1962-
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The cost and cycle time implications of selected contractor and Air Force system program office management policies during the development phase of a major aircraft acquisition programs [PDF]
, 1999 Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program; and (S.M.)--Massachusetts Institute of Technology, Sloan School of Management, 1999.Includes bibliographical references (leaves 111-113).by Séan Morgan.S ...
Morgan, Séan (Séan Padraig), 1961-
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source