Results 111 to 120 of about 2,618,617 (287)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Subject Index Volume 36 Nomor 2 Desember 2020

open access: yesJustitia Et Pax, 2020
Manager Justitia Et Pax
doaj   +1 more source

Maritime Trade, Biological Invasions, and the Properties of Alternate Inspection Regimes [PDF]

open access: yes
We analyze the problem of preventing biological invasions caused by ships transporting internationally traded goods between countries and continents. Specifically, we ask the following question: Should a port manager have a small number of inspectors ...
Amit Batabyal, Hamid Beladi, Won Koo
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

YÖNETİCİ VE YÖNETİCİLİK ÜZERİNE KAHRAMANMARAŞ KENTİNDE BİR ARAŞTIRMA

open access: yesSosyal Ekonomik Araştırmalar Dergisi, 2005
Sosyal, siyasal ve ekonomik gelişmelerin son derece hızlı yaşandığı günümüzde, yönetici ve yöneticilik anlayışı da önemli bir unsur haline gelmektedir. Gerçekten de çoğu kez yönetici ve yöneticilik anlayışı toplumsal gelişmelerin veya tersine toplumsal ...
Yakup Bulut, İsmail Bakan
doaj   +2 more sources

About this issue—vol 3, issue 2

open access: yesAustralasian Journal of Plastic Surgery, 2020
Journal Manager
doaj   +1 more source

INFORMATION GATHERING, DELEGATED CONTRACTING AND CORPORATE HIERARCHIES [PDF]

open access: yes
In a typical corporate hierarchy, the manager is delegated the authority to make strategic decisions, and to contract with other employees. We study when such delegation can be optimal.
Chongwoo Choe, In-Uck Park
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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