Results 131 to 140 of about 2,618,617 (287)

Conveying the Role of Professional Farm Managers to Potential Clientele [PDF]

open access: yes
Many farmland owners opt to work directly with farmer-tenants while others choose to hire a professional farm manager to assist in the management of their land.
Baird, George E., Griffin, Terry W.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Back Matter

open access: yesJurnal Inovasi dan Teknologi Pembelajaran, 2018
Journal Manager
doaj   +2 more sources

THE PARADIGM OF THE MANAGERIAL POSITION [PDF]

open access: yes
The aim of the present article is to introduce us into the complexity of themanagerial activity and of the managerial position. Since the interest of any organisation isto achieve efficient management, this objective would be impossible to meet without a
Larisa Dragolea, Moise Ioan Achim
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of Combined Interventions and Early Home Care Activation on 30-Day Hospital Readmissions: A Retrospective Observational Study. [PDF]

open access: yesMedicina (Kaunas)
Azzellino G   +6 more
europepmc   +1 more source

Too Few Cooks Spoil the Broth: Division of Labour and Directed Production [PDF]

open access: yes
How can a manager influence workers' activity while knowing little about it? This paper examines a situation where production requires several tasks, and the manager wants to direct production to achieve a preferred allocation of effort across tasks ...
Marisa Ratto, Wendelin Schnedler
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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