Results 161 to 170 of about 597,649 (305)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Password Manager

This thesis presents the development of a secure and user-friendly Django-based password manager application. It focuses on best practices in password management and cybersecurity, integrating cryptographic techniques to enhance security.
Uzukwu, Divine Onyedikachi
core  

Histomorphometrical Analyses of the Mouse Suprachiasmatic Nucleus. [PDF]

Bio Protoc
Villanueva SAMB, Lee FY, Hitchcock ON, Dell'Angelica EC, Colwell CS, Ghiani CA.   +5 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Challenges and enablers of collaborative working in the voluntary, community, social, faith and enterprise sector: impact, effectiveness, and sustainability. [PDF]

Front Public Health
Vincent BP, Ali N, Egbutah C, Perkins K.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Tips & Trends d. monatl. Informationsdienst von Manager-Magazin

, 1987

core  

Newborn screening results for sickle cell disease from the ASH Consortium on Newborn Screening in Africa (CONSA). [PDF]

Blood Adv
Awuonda BO, Kiyaga C, Chirande L, Franklin PC, Nnodu OE, Ambrose EE, Dogara LG, Chunda-Liyoka CM, Segbefia CI, Zapfel A, Benoit MA, Odame I, Tubman VN, Achebe MO, Thompson AA, Green NS, Berliner N, Novelli EM, Coetzer TL, Ware RE.   +19 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The figure of the nurse case manager in the management of disabled patients to undergo dental treatment

openIl tema trattato in questa tesi è il ruolo dell’infermiere case manager nella gestione dei pazienti con disabilità sottoposti a cure odontoiatriche.
MASSIMI, PIERPAOLO
core