Results 181 to 190 of about 597,649 (305)

From policies to promotion: managers' views on opportunities for alcohol prevention at work. [PDF]

Int J Qual Stud Health Well-being
Sundqvist K, Martinez M.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Manager unterwegs der monatliche Informationsdienst für Abonnenten von Manager-Magazin ; Reisetips aus erster Hand

, 1990

core  

Why does mutual fund performance not persist? The impact and interaction of fund flows and manager changes

This paper investigates the reasons for the lack of long-term persistence in the investment performance of actively managed equity mutual funds. We document that the responses of investors, fund managers, and investment management companies to past ...
Bessler, Wolfgang, Lückoff, Peter, Blake, David, Tonks, Ian   +3 more
core  

Managers perspectives on the implementation of the Prevention of Mother-to-Child Transmission policy in South Africa. [PDF]

J Public Health Afr
Dyeshana H, Zuma S.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

18. Ilmenauer TK-Manager Workshop: Technische Universität Ilmenau, 26. September 2025 : Tagungsband [PDF]

Telekommunikations-Manager e.V.
core   +1 more source

Managerial Social Wisdom: A major facet for Employee Turnover Intentions, Work Commitments and Manager-Subordinate Relationships

Working under a wise manager is incredibly worth it. There are some managers worth dying for and is a cast of ‘rare breed’. Leaders/Managers that have managerial wisdom, makes employees love to work long hours, exceed one’s abilities to perform just ...
Subhani, Muhammad Imtiaz, Hasan, Syed Akif   +1 more
core  

Sex differences in cancer incidence persist across race and ethnicity. [PDF]

Biol Sex Differ
Francis JJ, Katki HA, Graubard BI, Haiman CA, Marchand LL, Setiawan VW, Wilkens LR, Chaturvedi A, Jackson SS.   +8 more
europepmc   +1 more source