Results 41 to 50 of about 129,722 (297)
Africa’s Public Service Delivery & Performance Review, 2012 Local government has emerged from a prolonged transition to face a second generation of challenges, namely unfunded mandates. Compliance with the current financial management system is a constant challenge for local government.
M. Basdeo
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
D-Lib Magazine, 2007 This article is written mainly for repository managers who are at a loss as to what policies they (or their universities or research institutions) ought to deploy in order to ensure that most, if not all, of the institution's scholarly output is deposited in the institution's repository.
openaire +2 more sources
Administering Health Insurance Mandates [PDF]
, 2008 Provides an overview of health insurance mandates and administrative considerations. Based on a review of existing and proposed employer and individual mandates, outlines ways to structure them to be administered fairly and ...
C. Eugene Steuerle, Paul N. Van de Water
core +2 more sources
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
CONTEMPORARY U.S. FEDERALISM: COERCIVE CHANGE WITH COOPERATIVE CONTINUITY [PDF]
Revista d'Estudis Autonòmics i Federals, 2008 Contemporary U.S. federalism is a complex mixture of coercive, cooperative,and dual elements. Constitutionally and politically, the federal system hasbecome coercive because there has been a vast expansion of federal-governmentpower over the states since
John Kincaid
doaj
BMC Public Health, 2021 Background In the COVID-19 pandemic, Switzerland introduced broad nationwide face mask mandates only by October 2020, later than other Western European countries.
Bettina Maria Zimmermann +3 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Effects of Infertility Insurance Mandates on Fertility [PDF]
Infertility currently affects over 6 million individuals in the United States. While most health insurance plans nationwide do not cover infertility diagnoses or treatments, to date fifteen states have enacted some form of infertility insurance mandate ...
Lucie Schmidt
core +2 more sources
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source