Results 51 to 60 of about 61,229 (170)

Mandates and the Contributions of Open Genomic Data

Publications, 2013
This research attempts to seek changing patterns of raw data availability and their correlations with implementations of open mandate policies. With a list of 13,785 journal articles whose authors archived datasets in a popular biomedical data repository
Jingfeng Xia
doaj   +1 more source

State-level prescription drug monitoring program mandates and adolescent injection drug use in the United States, 1995-2017: A difference-in-differences analysis.

PLoS Medicine, 2020
BackgroundPrescription opioid misuse is an ongoing crisis and a risk factor for injection drug use (IDU). Few studies have evaluated strategies for preventing opioid or IDU initiation among adolescents.
Joel J Earlywine, Scott E Hadland, Julia Raifman   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Problems of substituting vacant deputy’s mandates due to early termination of powers of a deputy elected within a list of candidates

Известия высших учебных заведений. Поволжский регион: Общественные науки, 2022
Background. The distribution of deputy mandates after the end of the elections is one of the most controversial issues in legal science. The use of various methods of mandate distribution directly determines the implementation of electoral rights.
M.Yu. Emelin, B.V. Nikolaev
doaj   +1 more source

Efficacy of Generalized Face Masking Mandates

Health Services Research & Managerial Epidemiology, 2021
This commentary discusses if targeted uses of face masks may provide better results than generalized face masks mandates to limit the spread of Covid-19.
Alberto Boretti
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Mandates and social confrontation

, 2023
Datasets belonging to the manuscript "The presence of laws and mandates fosters social confrontation"
Tim Kurz, Laetitia Mulder, Miguel Fonseca, Annayah M.B. Prosser   +3 more
core   +3 more sources

Accuracy and precision in DM intake prediction models for lactating dairy cows

Animal
Predicting the daily DM intake (DMI) of lactating dairy cows is an essential criterion for formulating diets according to requirements, which limits the application of safety margins in economically and environmentally sensitive nutrients, such as energy,
N. Mehaba, S. Schrade, L. Eggerschwiler, F. Dohme-Meier, P. Schlegel   +4 more
doaj   +1 more source