Results 51 to 60 of about 514,928 (277)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Knowledge, attitudes and beliefs towards compulsory vaccination: a systematic review

Human Vaccines & Immunotherapeutics, 2019
Currently, many countries are dealing with groups refusing available recommended vaccinations. Despite several studies having demonstrated the efficacy of mandatory vaccinations in ensuring herd immunity, opposition is widespread.
MR Gualano, E Olivero, G Voglino, M Corezzi, P Rossello, C Vicentini, F Bert, R Siliquini   +7 more
doaj   +1 more source

A positive approach to parents with concerns about vaccination for the family physician [PDF]

, 2014
Provides an approach for primary care physicians to enable effective communication with parents who have different levels of concerns about vaccinations and awareness of currently available resources that may be used to support discussions.
Terry Nolan, Margie Danchin
core  

Healthcare workers’ views on mandatory SARS-CoV-2 vaccination in the UK: A cross-sectional, mixed-methods analysis from the UK-REACH study

EClinicalMedicine, 2022
Summary: Background: Several countries now have mandatory SARS-CoV-2 vaccination for healthcare workers (HCWs) or the general population. HCWs’ views on this are largely unknown.
Katherine Woolf, Mayuri Gogoi, Christopher A. Martin, Padmasayee Papineni, Susie Lagrata, Laura B. Nellums, I.Chris McManus, Anna L. Guyatt, Carl Melbourne, Luke Bryant, Amit Gupta, Catherine John, Sue Carr, Martin D. Tobin, Sandra Simpson, Bindu Gregary, Avinash Aujayeb, Stephen Zingwe, Rubina Reza, Laura J. Gray, Kamlesh Khunti, Manish Pareek   +21 more
doaj   +1 more source

BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi [PDF]

, 2011
BACKGROUND: BCG vaccination of infants is thought to provide good protection in all settings. This study investigated whether Malawian infants made weaker responses across a cytokine panel after BCG vaccination, compared with UK infants.METHODS: Diluted ...
Hazel M. Dockrell, Newport, Melanie J, Mvula, Hazzie, Weir, Rosemary E., Rose Blitz, Fine, P.E., Steven G. Smith, Nuala McGrath (230042), Crampin, Amelia C, Keith Branson (239422), Hazel M Dockrell (10414616), Sian Floyd, Fine, Paul E, Crampin, Amelia C., Weir, R.E., McGrath, N., Floyd, Sian, Rose Blitz (356877), Newport, M.J., Anne Ben-Smith (244056), Melanie Newport (4461202), Lalor, Maeve K., Hazzie Mvula, Lalor, M.K., Maeve K Lalor (16181825), Sian Floyd (239400), Weir, Rosemary E, Lalor, Maeve K, Gorak-Stolinska, P., Fine, Paul E., Nuala McGrath, Crampin, A.C., Ben-Smith, A., Steven G Smith (16181831), Maeve K. Lalor, Hazzie Mvula (271278), Smith, S.G., Mvula, H., Smith, Steven G., Smith, Steven G, Patricia Gorak-Stolinska (356875), Floyd, S., Blitz, R., McGrath, Nuala, Amelia C. Crampin, Gorak-Stolinska, Patricia, Rosemary E. Weir, Branson, K., Amelia C Crampin (10281422), Ben-Smith, Anne, Dockrell, Hazel M., Paul E. Fine, Paul E Fine (16181834), Blitz, Rose, Dockrell, H.M., Rosemary E Weir (16181828), Keith Branson, Anne Ben-Smith, Dockrell, Hazel M, Newport, Melanie J., Branson, Keith, Patricia Gorak-Stolinska, Melanie J. Newport   +62 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Is it ethical for immunisations against human papillomavirus to be mandatory in young people aged 12–13 years old?

Future Healthcare Journal
The discussion surrounding the ethics of mandatory HPV vaccination for young adolescents aged 12–13 is complex. The human papillomavirus (HPV) is a prevalent sexually transmitted infection with certain strains linked to cervical and other types of ...
Frenki Gjika
doaj   +1 more source

Manufacturing Consent for Vaccine Mandates: A Comparative Case Study of Communication Campaigns in France and Australia

Frontiers in Communication, 2021
Governments making childhood vaccination more mandatory is controversial, and can be met with pushback from the public. Hence such policies may be accompanied by some form of communication to manufacture consent for either vaccination, mandatory ...
Katie Attwell, Katie Attwell, Jeremy K. Ward, Jeremy K. Ward, Sian Tomkinson   +4 more
doaj   +1 more source

Vaccination status of children in Switzerland [PDF]

, 2007
Despite being recognized as one of the most effective public health measures, vaccination has become increasingly controversial as more parents and doctors question the effectiveness and purpose of this preventive measure, with heightened emphasis on ...
Lang, Phung
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source