Results 51 to 60 of about 35,398 (275)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mandatory vaccinations in European countries, undocumented information, false news and the impact on vaccination uptake: the position of the Italian pediatric society

Italian Journal of Pediatrics, 2018
Background High rates of vaccination coverage are important in preventing infectious diseases. Enforcing mandatory vaccinations is one of the strategies that some Countries adopted to protect the community when vaccination coverage is not satisfactory ...
Elena Bozzola, Giulia Spina, Rocco Russo, Mauro Bozzola, Giovanni Corsello, Alberto Villani   +5 more
doaj   +1 more source

Healthcare workers’ views on mandatory SARS-CoV-2 vaccination in the UK: A cross-sectional, mixed-methods analysis from the UK-REACH study

EClinicalMedicine, 2022
Summary: Background: Several countries now have mandatory SARS-CoV-2 vaccination for healthcare workers (HCWs) or the general population. HCWs’ views on this are largely unknown.
Katherine Woolf, Mayuri Gogoi, Christopher A. Martin, Padmasayee Papineni, Susie Lagrata, Laura B. Nellums, I.Chris McManus, Anna L. Guyatt, Carl Melbourne, Luke Bryant, Amit Gupta, Catherine John, Sue Carr, Martin D. Tobin, Sandra Simpson, Bindu Gregary, Avinash Aujayeb, Stephen Zingwe, Rubina Reza, Laura J. Gray, Kamlesh Khunti, Manish Pareek   +21 more
doaj   +1 more source

Manufacturing Consent for Vaccine Mandates: A Comparative Case Study of Communication Campaigns in France and Australia

Frontiers in Communication, 2021
Governments making childhood vaccination more mandatory is controversial, and can be met with pushback from the public. Hence such policies may be accompanied by some form of communication to manufacture consent for either vaccination, mandatory ...
Katie Attwell, Katie Attwell, Jeremy K. Ward, Jeremy K. Ward, Sian Tomkinson   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Is it ethical for immunisations against human papillomavirus to be mandatory in young people aged 12–13 years old?

Future Healthcare Journal
The discussion surrounding the ethics of mandatory HPV vaccination for young adolescents aged 12–13 is complex. The human papillomavirus (HPV) is a prevalent sexually transmitted infection with certain strains linked to cervical and other types of ...
Frenki Gjika
doaj   +1 more source

A positive approach to parents with concerns about vaccination for the family physician [PDF]

, 2014
Provides an approach for primary care physicians to enable effective communication with parents who have different levels of concerns about vaccinations and awareness of currently available resources that may be used to support discussions.
Terry Nolan, Margie Danchin
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mapping the Global Adoption of Mandatory Vaccination against COVID-19: A Scoping Review

Journal of Respiration, 2023
The coronavirus (COVID-19) pandemic caused sicknesses ranging from mild to deadly, which disrupted lives and healthcare systems across the globe. Despite the availability of vaccines that are effective in significantly reducing the risks of death and ...
Jessica U. Damian, Takalani G. Tshitangano   +1 more
doaj   +1 more source