Results 61 to 70 of about 514,928 (277)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Mandatory Influenza Vaccination for Healthcare Workers: Do Nurses Agree? [PDF]

, 2013
Influenza is a significant cause of morbidity and mortality among hospitalized patients. Health care workers are considered a high-risk group for influenza, and annual vaccination is the most effective way to prevent getting influenza. Increasing concern
Meghan Nightingale, Nightingale, Meghan Leah   +1 more
core   +1 more source

The Willingness toward Vaccination: A Focus on Non-Mandatory Vaccinations

Vaccines, 2023
The Special Issue “The Willingness toward Vaccination: A Focus on Non-mandatory Vaccinations”, published in the journal Vaccines, has the main aim of gathering more data on vaccine hesitancy and the willingness of individuals to receive vaccinations, particularly in the context of non-mandatory vaccines.
Angelo Capodici, Francesco Sanmarchi, Nicole Bonaccorso, Claudio Costantino, Elisa Maietti   +4 more
openaire   +6 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Ethics of Vaccination: Mandatory vaccination

, 2022
V človeški zgodovini so bile nalezljive bolezni in epidemični izbruhi glavni vzroki smrti. Za omejitev širjenja nalezljive bolezni je potrebno doseči kolektivno imunost, ki pa jo danes lahko, po zaslugi moderne medicine, hitreje dosežemo s cepljenjem ...
Junkar, Klara
core  

Parental attitudes towards mandatory vaccination of children [PDF]

, 2023
Diplomová práce pojednává o problematice postojů rodičů k povinnému očkování dětí. Cílem práce byla analýza současných postojů rodičů k přijímání či odmítání povinného očkování dětí v České republice.
Karolína Červenková
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Mapping the Global Adoption of Mandatory Vaccination against COVID-19: A Scoping Review

Journal of Respiration, 2023
The coronavirus (COVID-19) pandemic caused sicknesses ranging from mild to deadly, which disrupted lives and healthcare systems across the globe. Despite the availability of vaccines that are effective in significantly reducing the risks of death and ...
Jessica U. Damian, Takalani G. Tshitangano   +1 more
doaj   +1 more source

Correlates of Complete Childhood Vaccination in East African Countries. [PDF]

, 2014
Despite the benefits of childhood vaccinations, vaccination rates in low-income countries (LICs) vary widely. Increasing coverage of vaccines to 90% in the poorest countries over the next 10 years has been estimated to prevent 426 million cases of ...
Kassie, Getnet M, Elizabeth H Bradley, Getnet M Kassie, Bradley, Elizabeth H, Canavan, Maureen E, Maureen E Canavan, Heather L Sipsma, Bradley Elizabeth H., Sipsma, Heather L, Kassie Getnet M., Canavan Maureen E., Sipsma Heather L.   +11 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source