Results 31 to 40 of about 16,002 (283)

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Penatalaksanaan fraktur kondilus bilateral dan korpus mandibula dengan reduksi tertutup pada pasien remaja

Management of bilateral condyle fracture and mandibular corpus with the closed reduction in adolescent patients

Jurnal Kedokteran Gigi Universitas Padjadjaran, 2022
ABSTRAK Pendahuluan: Fraktur kondilus dan Korpus mandibula merupakan fraktur pada mandibula yang cukup sering terjadi pasca trauma. Komplikasi yang sering terjadi akibat fraktur kondilus dan korpus mandibula pada anak adalah ankilosis dan gangguan sendi
Deny Rakhman, Farah Asnely Putri, Fathurachman Fathurachman, Endang Sjamsudin   +3 more
doaj   +1 more source

Pembuatan Filamen Biodegradasi Printer 3d Metode Fused Deposition Modelling dari Polimer Sintesis dan Hidroksiapatite Bovine untuk Implan Scaffolds Rekonstruksi Mandibula [PDF]

, 2016
Penyebab kematian di dunia salah satunya penyakit kanker dan menyumbang sekitar 0.2% dari jumlah kasus kanker. Setiap tahun tidak kurang dari 240.000 kasus kanker tulang terjadi di Indonesia, terdiri dari dari tumor jinak dan tumor ganas.
Anwar, S. A. (Saifudin), Solechan, S. (Solechan)   +1 more
core  

Primata besar di Jawa: spesimen baru gigantopithecus dari Semedo [PDF]

, 2016
Pada tahun 2014 ditemukan dua spesimen mandibula yang ”enigmatic”, dengan nama Semedo 3417 dan Semedo 3418. Kedua mandibula tersebut secara morfologis mirip dengan bentuk rahang primata pada umumnya, namun berukuran dua kali lipat lebih besar.
Noerwidi, Sofwan, Siswanto, Siswanto, Widianto, Hary   +2 more
core   +2 more sources

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Fraturas odontomaxilares e mandibulares em eqüídeos tratados por diferentes técnicas de osteossíntese Odontomaxillares and mandibularies fractures in equides treated with different osteosynthesis techniques

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2008
Oito eqüinos e um muar com fraturas odontomaxilares e mandibulares foram tratados com diferentes técnicas de osteossíntese modificadas, consistindo de cerclagens associadas ou não a bandas de tensão, placa de neutralização e pino intraosseo, sendo este ...
G.E.S. Alves, G.M. Pagliosa, H.P. Oliveira, V.A. Gheller, R.R. Faleiros   +4 more
doaj   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Cinsiyetin mandibuler parametreler üzerine etkisi: Retrospektif KIBT çalışması

Selcuk Dental Journal, 2019
Amaç: Kafatasının en geniş, en sert ve en hareketli kemiği olan mandibulanın tanımlanması pelvis ve kafatasından sonra cinsiyetler arasında en çok fark gözlenen kemik olması sebebiyle medikolegal ve antraopolojik açıdan önemlidir.
Derya İçöz, Faruk Akgünlü
doaj  

Alveolar ridge rehabilitation to increase full denture retention and stability

Dental Journal, 2010
Background: Atrophic mandibular alveolar ridge generally complicates prostetic restoration expecially full denture. Low residual alveolar ridge and basal seat can cause unstable denture, permanent ulcer, pain, neuralgia, and mastication difficulty.
Mefina Kuntjoro, Rostiny Rostiny, Wahjuni Widajati   +2 more
doaj   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source