Results 51 to 60 of about 273 (136)

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux   +7 more
wiley   +1 more source

Gq Signaling in Microglia Triggers Interferon Responses and Improves Outcome After Ischemic Stroke

open access: yesGlia, Volume 74, Issue 10, October 2026.
Chemogenetic activation of Gq signaling in microglia ahead of ischemic stroke reduces infarct size in mice. Seven days after stroke, Gq‐primed microglia in the penumbra show enhanced interferon responses, altered branching patterns, and reduced phagocytosis.
Lynn Bitar   +8 more
wiley   +1 more source

A Comparison of Tissue Property Values Estimated Using Conventional Cardiac MRF and MT‐Cardiac MRF

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1806-1813, October 2026.
ABSTRACT Purpose To evaluate the impact of explicitly modeling Magnetization Transfer (MT) during reconstruction of cardiac Magnetic Resonance Fingerprinting (cMRF) maps on T1 and T2 quantification. Methods cMRF data were reconstructed using two dictionaries: a conventional cMRF dictionary that ignores MT processes, and an MT‐cMRF dictionary modeling ...
Sydney Kaplan   +7 more
wiley   +1 more source

Toward Hierarchical Assembly of Aligned Cell Sheets into a Conical Cardiac Ventricle Using Microfabricated Elastomers. [PDF]

open access: yesAdv Biol (Weinh), 2022
Mohammadi MH   +11 more
europepmc   +1 more source

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

open access: yesGlia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans   +39 more
wiley   +1 more source

Rapid-dissolving electrospun nanofibers for intra-vaginal antibiotic or probiotic delivery. [PDF]

open access: yesEur J Pharm Biopharm, 2023
Minooei F   +12 more
europepmc   +1 more source

3D MR Fingerprinting for Quantitative Bladder Wall T1, T2, and M0 Mapping in Healthy Subjects at 1.5 T and 3 T

open access: yesNMR in Biomedicine, Volume 39, Issue 9, September 2026.
Current diagnostic tests for lower urinary tract symptoms lack the ability to assess tissue‐level alterations in the bladder wall. This study introduces an approach for simultaneous high‐resolution 3D T1, T2, and proton density mapping of the bladder wall using magnetic resonance fingerprinting combined with a self‐supervised deep learning ...
Shane A. Wells   +5 more
wiley   +1 more source

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