Results 31 to 40 of about 80,998 (294)

Is the Concept of Delirious Mania Valid in the Elderly? A Case Report and a Review of the Literature

Case Reports in Psychiatry, 2013
Delirious mania has been well recognized in the published literature and in the clinic. Over the years there has been refinement of understanding of its clinical features, course, and treatment.
Pramudith M. Maldeniya, Akshya Vasudev
doaj   +1 more source

Assessing positive and negative valence systems to refine animal models of bipolar disorders: the example of GBR 12909-induced manic phenotype

Scientific Reports, 2022
Bipolar disorders are defined by recurrences of depressive and manic episodes. The pathophysiology is still unknown, and translating clinical symptoms into behaviors explorable in animal models is challenging.
Mathilde Bigot, Eleonore Vicq, Pierre-Marie Lledo, Mariana Alonso, Chantal Henry   +4 more
doaj   +1 more source

Diverse Pathophysiological Processes Converge on Network Disruption in Mania

bioRxiv, 2018
Background Neuroimaging of psychiatric disease is challenged by the difficulty of establishing the causal role of neuroimaging abnormalities. Lesions that cause mania present a unique opportunity to understand how brain network disruption may cause mania
Ivy Lee, K. Nielsen, M. Hall, D. Öngür, M. Keshavan, R. Brady   +5 more
semanticscholar   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

Advanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan, Yinfeng Lyu, Yi Liu, Jianping Ren, Yue Zhao, Licong Zhang, Anshan Shan   +6 more
wiley   +1 more source

Educational leaders' reports of conditions for supporting SEL implementation: The power of partnerships

American Journal of Community Psychology, EarlyView.
Abstract Well‐implemented social and emotional learning (SEL) programs are associated with positive student outcomes. Through CalHOPE, County Office of Education (COE) leaders are providing implementation support to districts and schools seeking to improve SEL delivery statewide.
Ashley N. Metzger, Justin D. Caouette, Tiffany M. Jones, CalHOPE Research Committee, Valerie B. Shapiro   +4 more
wiley   +1 more source

Behavioral manifestations and underlying mechanisms of amphetamine in constructing animal models of mania: a comprehensive review

Frontiers in Neuroscience
Mania is a mind disorder with heightened emotions, etc. Amphetamine (AMPH), a drug with central nervous system excitatory effects, can disrupt neurotransmitter release and metabolism, causing mania. AMPH-induced animal models of mania show increased risk
Zi-Qi Deng, Zi-Qi Deng, Xiao-Chen Si, Jia-Bin Song, Jin-Yao Li, Lu Sun, Xue Dang, Min Zhao, Yan-Chen Feng, Yan-Chen Feng, Fei-Xiang Liu   +10 more
doaj   +1 more source

Brain-derived neurotrophic factor protein and mRNA levels in patients with bipolar mania – A preliminary study

Biomedical Journal, 2016
Background: Brain-derived neurotrophic factor (BDNF) protein or mRNA levels may be involved in the pathophysiology of bipolar disorder. However, the results were inconsistent.
Chin-Chuen Lin, Chien-Te Lee, Ya-Ting Lo, Tiao-Lai Huang   +3 more
doaj   +1 more source

The Impact of the Parental Patterns of Morbidity and Comorbidity in the Cross‐Generational Transmission of Risk for Major Depression and Alcohol Use Disorder

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT To further understand the inter‐relationship of the familial transmission of major depression (MD) and alcohol use disorder (AUD), we examine, via a multivariable Cox proportional hazards model, risks for AUD and MD in 1,244,516 individuals born in Sweden from 1970 to 1990 to intact mother–father pairs as a function of parental diagnoses of MD
Kenneth S. Kendler, Linda Abrahamsson, Jan Sundquist, Kristina Sundquist   +3 more
wiley   +1 more source

Rüdin's Unpublished Family Study From the Early 1920s: “On the Inheritance of Manic‐Depressive Insanity”

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Ernst Rüdin, an important and controversial figure in the history of psychiatric genetics, published only one major empirical study on siblings of dementia praecox (DP) probands in 1916. He conducted a parallel study of siblings of probands with manic‐depressive insanity (MDI), but the resulting monograph, written in the early 1920s, was left ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source