Results 91 to 100 of about 23,105 (194)

The Effect of Benzodiazepines on Catatonia: A Systematic Review and Meta‐Analysis

open access: yesActa Psychiatrica Scandinavica, Volume 154, Issue 2, Page 99-115, August 2026.
ABSTRACT Introduction Catatonia is a complex psychomotor syndrome associated with various psychiatric and somatic underlying disorders. Current treatment protocols include benzodiazepines and electroconvulsive therapy (ECT). Despite their widespread use, systematic evidence regarding efficacy and optimal benzodiazepine dosage remains limited.
L. Bot   +14 more
wiley   +1 more source

Biofluid Biomarkers of Cognitive Functioning in Bipolar Disorder: A Systematic Review by the Targeting Cognition and Older‐Age Bipolar Disorder ISBD Task Forces

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently with cognition in BD ...
Alexandra J. M. Beunders   +21 more
wiley   +1 more source

Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Clinicians aspire to predict the emergence of Bipolar Disorder (BD) in a timely manner. To accomplish this, markers reflecting mental states that can be gathered non‐invasively and at large scale are needed. Here, we systematically evaluate evidence relating speech‐based markers to mood states in BD.
Farida Zaher   +4 more
wiley   +1 more source

Psychotropic Prescribing Patterns Among Bipolar‐I Patients Prior to Established Bipolar‐I Disorder Diagnosis

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objective Bipolar I Disorder (BP‐I) is frequently misdiagnosed as Major Depressive Disorder (MDD), delaying appropriate treatment. This study aimed to examine treatment patterns among BP‐I patients misdiagnosed with MDD and assess the impact of these regimens on the time until BP‐I diagnosis.
Filmon Haile   +2 more
wiley   +1 more source

Can We Improve the Prediction of Early Onset Mania and Hypomania in the Community?

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background There is broad agreement that the onset of bipolar disorders (BD) can be predicted by using combined estimates of familial, genetic and clinical risk. However, there is a lack of consensus about the operationalisation of different risk attributes (e.g., symptoms vs.
Jan Scott   +6 more
wiley   +1 more source

Essential Information About Chronobiology and Chronotherapy for the Optimal Care of People With Bipolar Disorders: An Expert Consensus

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Introduction Circadian dysfunction is involved in the pathophysiology of bipolar disorders (BD), and circadian‐based interventions are gaining recognition in their management. Moreover, basic and epidemiologic research has generated findings inspiring circadian‐informed self‐ and clinician‐management strategies.
Jacob J. Crouse   +40 more
wiley   +1 more source

Epigenetic Age Accelerations and the Clinical Presentation of Bipolar Disorders: A Latent Profile Analysis in the FACE‐BD Sample

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Epigenetic age accelerations have been associated with the clinical expression of BD; however, with few available studies. Method We calculated Horvath, Hannum, EN, GrimAge, and PhenoAge epigenetic ages in a sample of 139 individuals with BD.
Luana Spano   +92 more
wiley   +1 more source

The Theory of Metabolic Jet Lag in Bipolar Disorder: A Pilot Feasibility Study Exploring the Association Between Eating Rhythm Disruption and Illness Burden Parameters

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Introduction Changes in energy metabolism are commonly observed in bipolar disorder (BD) and have been linked to a more severe clinical course. ‘Metabolic jet lag’ (MJL) is a state of shift in circadian patterns of energy homeostasis, expressed through behavioral changes such as irregular meal timing.
Elena Koning   +3 more
wiley   +1 more source

Time Trends in Excess Mortality Among Individuals With Bipolar Disorder in Finland, 2000–2023: A Nationwide Register Study

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives To investigate excess all‐cause mortality among individuals with bipolar disorder in Finland and examine time trends in the mortality gap between individuals with bipolar disorder and the general population during 2000–2023. Methods Individuals diagnosed with bipolar disorder during 1975–2023 in Finland were identified using the ...
Julia Rimmington   +5 more
wiley   +1 more source

Smoking Initiation, Age at Onset of Symptoms and Suicide Attempts Among Patients With Bipolar Disorder: Comparisons With Non‐Psychiatric Adults

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Introduction The prevalence of tobacco smoking and high nicotine dependence (ND) in bipolar disorder (BD) is higher than in the general population but lower than in schizophrenia. This study aims to analyse the relationship of smoking behaviours, including age at onset of daily smoking (AODS), with age at onset of BD and course‐of‐illness ...
Manuel Gurpegui   +6 more
wiley   +1 more source

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