Results 41 to 50 of about 586,134 (220)

Multidimensional analysis of heart rate variability and burden of illness in bipolar disorder

Psychiatry Research Communications
Introduction: Patients with bipolar disorder (BD) face disproportionate rates of cardiovascular disease. While several mechanisms have been proposed for this association, both are multifactorial and heterogeneous illnesses, and it is unlikely that any ...
Abigail Ortiz, Milos Milic, Marcos Sanches, M. Ishrat Husain, Benoit H. Mulsant, Daniel Felsky   +5 more
doaj   +1 more source

Ten‐year course of treated bipolar I disorder: The role of polarity at onset

Brain and Behavior, 2021
Introduction Early‐stage predictors of illness course are needed in bipolar disorder (BD). Differences among patients with a first depressive versus maniac/hypomanic episode have been stated, although in most studies, memory bias and time from onset to ...
María Yoldi‐Negrete, Ana Fresán‐Orellana, Mariana Jiménez‐Tirado, Sara Martínez‐Camarillo, Lino Palacios‐Cruz, Eduard Vieta, Hiram Ortega‐Ortiz, Claudia Becerra‐Palars, Doris Gutiérrez‐Mora, Beatriz Camarena Medellín   +9 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Epidemiology and heritability of Major Depressive Disorder, stratified by age of onset, sex, and illness course in Generation Scotland:Scottish Family Health Study (GS:SFHS) [PDF]

, 2015
The heritability of Major Depressive Disorder (MDD) has been estimated at 37% based largely on twin studies that rely on contested assumptions. More recently, the heritability of MDD has been estimated on large populations from registries such as the ...
Andrew G. McKechanie (827281), Ana Maria Fernandez-Pujals, Mark James Adams (3272922), Matthews Keith, Chris S Haley, Mark James Adams, Morris, Andrew D., Morris, Andrew D, Pippa Thomson, Campbell Archie, MacIntyre, Donald J; id_orcid, Anna F Dominiczak, MacIntyre Donald J., Andrew G McKechanie, Andrew M McIntosh, Ana Maria Fernandez-Pujals (827280), Thomson, Pippa; id_orcid, Fernandez-Pujals, Ana Maria, Pippa Thomson (759189), MacIntyre, Donald J., McIntosh Andrew M., Pamela Linksted (787794), David J Porteous, Adams, Mark James; id_orcid, Campbell, Archie, Chris S. Haley (208845), Keith Matthews (22202), Morris Andrew D., Smith, Blair H.; id_orcid, Andrew M. McIntosh (292147), Blackwood, Douglas H R, David J. Porteous (107720), Ian J. Deary (107724), Andrew D Morris, Andrew D. Morris (130204), Matthews, Keith, Haley, Chris S., Adams, Mark James, McKechanie, Andrew G; id_orcid, Deary, Ian J., Smith Blair H., Porteous, David J, Ian J Deary, McKechanie, Andrew G., Blair H Smith, Thomson, Pippa, Blackwood, Douglas H. R., Smith, Blair H, Donald J. MacIntyre (827282), Linksted Pamela, McIntosh, Andrew M., Archie Campbell (669891), Ebmeier, Klaus, McIntosh, Andrew M; id_orcid, Archie Campbell, Deary, Ian J, Douglas H. R. Blackwood (759192), McKechanie Andrew G., Blair H. Smith (625812), Fernandez-Pujals Ana Maria, Keith Matthews, Linksted, Pamela, Anna F. Dominiczak (238664), Blackwood Douglas H. R., Smith, Blair H., Porteous, David J., Dominiczak, Anna F, Haley, Chris S, Dominiczak, Anna, Haley Chris S., Deary Ian J., Donald J MacIntyre, Thomson Pippa, Pamela Linksted, Dominiczak, Anna F., Porteous David J., Douglas H R Blackwood, Adams Mark James, Dominiczak Anna F.   +78 more
core   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Manic-Depressive Illness [PDF]

JAMA: The Journal of the American Medical Association, 1970
If one can agree to these authors' broad definition of affective disorder, one cannot fail to be impressed with their finding that affective disorders occur three times as frequently as schizophrenia in the general population. The authors comprehensively review the diverse findings of epidemiological surveys and studies subclassifying the affective ...
  +4 more sources

Feeling Better Before, Not After: An Ecological Momentary Assessment of Affect Around Exercise in Women With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Maladaptive exercise includes excessive, compulsive, or compensatory exercise and is a common eating‐disorder (ED) symptom associated with increased severity, slower rates‐of‐recovery, and faster rates‐of‐relapse. Affect‐regulation theories posit that maladaptive exercise functions to reduce high negative affect (NA), although ...
Danielle A. N. Chapa, Kelsie T. Forbush, Yiyang Chen, Courtney E. Costain, Samiya I. Rasheed   +4 more
wiley   +1 more source

Prevalence and association of comorbid substance dependence on the course and outcome of bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study)

Indian Journal of Psychiatry, 2022
Aim: To evaluate the prevalence of substance use disorder (SUD) and its association with the course and outcome of bipolar disorder (BD). Materials and Methods: A total of 773 patients with BD were recruited from 14 centers in different parts of India ...
Sandeep Grover, Ajit Avasthi, Rahul Chakravarty, Amitava Dan, Kaustav Chakraborty, Rajarshi Neogi, Avinash Desouza, Omkar Nayak, Samir Praharaj, Vikas Menon, Raman Deep, Manish Bathla, Alka A. Subramanyam, Naresh Nebhinani, Prosenjit Ghosh, Bhavesh Lakdawala, Ranjan Bhattacharya   +16 more
doaj   +1 more source

Humanism in the Age of Hyperreality: A Speculative Critique of AI Therapybots and the Neoliberal Commodification of Human Beings

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This article examines the future place of humanistic counseling, assuming the successful mass deployment of artificial intelligence therapy chatbots (AITCs). We systematically identify the limitations of AITCs through the lens of Jean Baudrillard's view on simulacra and hyperreality and identify five collective psychosocial consequences of ...
Brett. D. Wilkinson, Andrew M. Brown
wiley   +1 more source

Phosphoinositide metabolism, lithium and manic depressive illness

, 2002
Physiology underlying manic depressive illness and treating effects of its most commonly used remedy - "lithium" is yet to be elucidated. Recent years of psychopharmacology research witnessed sparkling developments in our understanding of the mechanisms ...
Yildiz, A
core   +1 more source