Results 131 to 140 of about 76,451 (278)

Immune Dysregulation in Bipolar Disorder: The Role of IL-27 and EBI3

BJPsych Open
Aims: Bipolar disorder (BD) is a severe psychiatric illness characterized by alternating depressive and manic episodes. The exact cause of BD remains unclear, but inflammatory and immunological processes are believed to play a significant role in its ...
Golnaz Sheykhnazari, Maliheh Ziaee, Ezinne Ijeoma Onuba, Najmeh Shahini, Yaser Bagheri   +4 more
doaj   +1 more source

Antidepressant-induced Dopamine Receptor Dysregulation: A Valid Animal Model of Manic-Depressive Illness. [PDF]

Curr Neuropharmacol, 2017
Demontis F, Serra F, Serra G.
europepmc   +1 more source

Linkage between glucose-6-phosphate dehydrogenase deficiency and manic-depressive psychosis.

, 1980
Hereditary has been shown to be an important factor in the aetiology of manic-depressive psychosis. Recent linkage studies with colour blindness have suggested the presence of an X-linked dominant gene in the transmission of manic-depressive psychosis ...
Mendlewicz, Julien, Linkowski, Paul, Wilmotte, Jean   +2 more
core  

Trajectories of Suicidal Risk Impact Mood Regulation Differently in Patients With a Diagnosis of Bipolar Disorder

Acta Psychiatrica Scandinavica, Volume 154, Issue 1, Page 60-73, July 2026.
ABSTRACT Background Bipolar disorder (BD) carries a suicide risk 20 times higher than the general population, with up to 60% of patients attempting suicide. Current interventions have failed to reduce its incidence; static factors have shown limited predictive utility.
Abigail Ortiz, Ramzi Halabi, Daniel Blumberger, Christina Gonzalez‐Torres, Arend Hintze, Muhammad I. Husain, Mirkamal Tolend, Juveria Zaheer, Martin Alda, Benoit H. Mulsant   +9 more
wiley   +1 more source

Changes over time in hallucinogen‐related emergency department visits in Ontario, Canada

Addiction, Volume 121, Issue 7, Page 1781-1793, July 2026.
Abstract Background and aims Recent increasing interest in hallucinogens has underscored the critical gaps in our understanding of their adverse health effects and healthcare usage over time. The current study aimed to examine changes in emergency department (ED) visit rates involving hallucinogens, clinical outcomes of visits and the characteristics ...
Daniel T. Myran, Rachael MacDonald‐Spracklin, Alexander R. Levesque, Michael Pugliese, Jess G. Fiedorowicz, André J. McDonald, Joshua D. Rosenblat, Ian Colman, Josephine Zein, Marco Solmi   +9 more
wiley   +1 more source

Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients.

, 2010
Background: There is an increasing evidence that the Brain-Derived Neurotrophic Factor (BDNF) could be involved in the pathophysiology of mood disorders and that its peripheral levels may represent a reliable mirror of its concentration in the brain. The
BIANCHI, CAROLINA
core  

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Associations of Serum Cytokine Receptor Levels with Melancholia, Staging of Illness, Depressive and Manic Phases, and Severity of Depression in Bipolar Disorder

, 2017
Associations of Serum Cytokine Receptor Levels with Melancholia, Staging of Illness, Depressive and Manic Phases, and Severity of Depression in Bipolar ...
M Siwek (13353495), D Dudek (10825035), K Styczeń (13353501), G Nowak (13330761), RJ Nowak (15835448), M Maes (13320648), M Sowa-Kućma (13353498), B Szewczyk (13330575), JK Rybakowski (14465862), P Misztak (13353504)   +9 more
core  

Narrative Review of Catatonia in Psychosis and Eating Disorders: Common Intersections and Treatment Considerations

Early Intervention in Psychiatry, Volume 20, Issue 7, July 2026.
ABSTRACT Background Eating disorders (ED) and psychosis/psychotic‐spectrum disorders (PSD) have overlapping symptoms and may co‐occur in a variety of presentations. Due to its debilitating and life‐threatening risk, it is important for clinicians to be aware of how catatonia may present within these co‐occurrences.
Rosiel Elwyn
wiley   +1 more source

Immune dysregulation in mania: A proof‐of‐concept platelet proteomics study

Psychiatry and Clinical Neurosciences, Volume 80, Issue 7, Page 575-584, July 2026.
Aims Bipolar disorder (BD) is a major psychiatric condition with a multifaceted and largely unknown pathophysiology. Mania, the defining feature of BD, remains underinvestigated. Proteomics offers a powerful, data‐driven, unbiased approach to uncover biological alterations.
Paola Magioncalda, Matteo Martino, Nhi Thao Ngoc Le, Wen‐Yin Chen, Ming‐Chyi Huang, David Blum, Thierry Burnouf   +6 more
wiley   +1 more source