Results 31 to 40 of about 24,090 (182)

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Prevalence and association of comorbid substance dependence on the course and outcome of bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study)

Indian Journal of Psychiatry, 2022
Aim: To evaluate the prevalence of substance use disorder (SUD) and its association with the course and outcome of bipolar disorder (BD). Materials and Methods: A total of 773 patients with BD were recruited from 14 centers in different parts of India ...
Sandeep Grover, Ajit Avasthi, Rahul Chakravarty, Amitava Dan, Kaustav Chakraborty, Rajarshi Neogi, Avinash Desouza, Omkar Nayak, Samir Praharaj, Vikas Menon, Raman Deep, Manish Bathla, Alka A. Subramanyam, Naresh Nebhinani, Prosenjit Ghosh, Bhavesh Lakdawala, Ranjan Bhattacharya   +16 more
doaj   +1 more source

Beyond BMI: Unsupervised Machine Learning Clustering of Bioelectrical Impedance Phenotypes Is Associated With Weight‐Recovery Trajectories in Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To identify data‐driven body composition phenotypes in patients with moderate‐to‐extreme anorexia nervosa (AN) using machine learning (ML) clustering of bioelectrical impedance analysis (BIA) parameters, and to test whether these phenotypes have specific psychopathological and childhood trauma profiles while correlating with early ...
Emanuele Cassioli, Gaia Maiolini, Eleonora D'Areglia, Livio Tarchi, Eleonora Rossi, Veronica Ceccarelli, Cristiano Dani, Luca Zompa, Chiara Ranieri, Enrico Lodovici, Anita Nannoni, Valdo Ricca, Giovanni Castellini   +12 more
wiley   +1 more source

Exploring the predictive role of the first mood episode on the predominant polarity in bipolar disorder: insights from a path analysis

Annals of General Psychiatry
Background The predominant polarity in bipolar disorder (BD) is defined by the skewness of mood episodes towards either the manic or depressive pole. However, since the predominant polarity can only be established over the long term, it is crucial to ...
Daniele Cavaleri, Cristina Crocamo, Ilaria Riboldi, Federica Boniello, Bianca Clerici, Martina Molendini, Giuseppe Carrà, Francesco Bartoli   +7 more
doaj   +1 more source

Correlates and Predictors of Binge Eating Disorder in Male Populations: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This PRISMA‐compliant systematic review synthesises empirical literature on correlates and predictors of DSM‐5/DSM‐IV Binge Eating Disorder (BED) in male populations (PROSPERO: CRD420250644500). Method Eligible studies used male‐only samples, sex‐stratified analyses, or comparisons involving men with BED.
Sharon L. Grant, Kathleen De Boer
wiley   +1 more source

A historical construction of the phenomenon of mania in the field of psychopathology [PDF]

Revista Latinoamericana de Psicopatologia Fundamental
This study aims to shed light on the construction of the concept of mania in the field of psychopathology. The article addresses the historical evolution of mania, from manic-depressive illness to the diagnosis of bipolar and schizoaffective disorders ...
Juliana Lima de Araújo, Virginia Moreira   +1 more
doaj   +1 more source

Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders

Scientific Reports, 2023
Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in mental disorders.
Monica Aas, Ole A. Andreassen, Johannes Gjerstad, Linn Rødevand, Gabriela Hjell, Ingrid Torp Johansen, Synve Hoffart Lunding, Monica B. E. G. Ormerod, Trine V. Lagerverg, Nils Eiel Steen, Srdjan Djurovic, Ibrahim Akkouh   +11 more
doaj   +1 more source

The TIMEBASE Study: IdenTifying dIgital bioMarkers of illnEss activity in BipolAr diSordEr. Preliminary results

European Psychiatry, 2022
Introduction Mood episodes in bipolar disorder (BD) are still identified with subjective retrospective reports and scales. Digital biomarkers, such as actigraphy, heart rate variability, or ElectroDermal activity (EDA) have demonstrated their potential ...
G. Anmella, A. Mas, I. Pacchiarotti, T. Fernández, A. Bastidas, I. Agasi, M. Garriga, N. Verdolini, N. Arbelo, D. Nicolás, V. Ruiz, M. Valentí, A. Murru, E. Vieta, A. Solanes, F. Corponi, B. Li, D. Hidalgo-Mazzei   +17 more
doaj   +1 more source