Results 41 to 50 of about 724,586 (214)

Ten‐year course of treated bipolar I disorder: The role of polarity at onset

open access: yesBrain and Behavior, 2021
Introduction Early‐stage predictors of illness course are needed in bipolar disorder (BD). Differences among patients with a first depressive versus maniac/hypomanic episode have been stated, although in most studies, memory bias and time from onset to ...
María Yoldi‐Negrete   +9 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

Making sense of depressive symptoms associated with stroke: A Q methodological study [PDF]

open access: yes, 2012
This thesis aimed to investigate depressive symptoms associated with stroke. Depression related to stroke is highly prevalent, not easy to diagnose, with important consequences for prognosis.
Rowbottom, Carrie Lynn
core   +6 more sources

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi   +6 more
wiley   +1 more source

Manic-Depressive Illness [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1970
If one can agree to these authors' broad definition of affective disorder, one cannot fail to be impressed with their finding that affective disorders occur three times as frequently as schizophrenia in the general population. The authors comprehensively review the diverse findings of epidemiological surveys and studies subclassifying the affective ...
  +4 more sources

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

Prevalence and association of comorbid substance dependence on the course and outcome of bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study)

open access: yesIndian Journal of Psychiatry, 2022
Aim: To evaluate the prevalence of substance use disorder (SUD) and its association with the course and outcome of bipolar disorder (BD). Materials and Methods: A total of 773 patients with BD were recruited from 14 centers in different parts of India ...
Sandeep Grover   +16 more
doaj   +1 more source

Feeling Better Before, Not After: An Ecological Momentary Assessment of Affect Around Exercise in Women With Eating Disorders

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Maladaptive exercise includes excessive, compulsive, or compensatory exercise and is a common eating‐disorder (ED) symptom associated with increased severity, slower rates‐of‐recovery, and faster rates‐of‐relapse. Affect‐regulation theories posit that maladaptive exercise functions to reduce high negative affect (NA), although ...
Danielle A. N. Chapa   +4 more
wiley   +1 more source

Exploring the predictive role of the first mood episode on the predominant polarity in bipolar disorder: insights from a path analysis

open access: yesAnnals of General Psychiatry
Background The predominant polarity in bipolar disorder (BD) is defined by the skewness of mood episodes towards either the manic or depressive pole. However, since the predominant polarity can only be established over the long term, it is crucial to ...
Daniele Cavaleri   +7 more
doaj   +1 more source

Humanism in the Age of Hyperreality: A Speculative Critique of AI Therapybots and the Neoliberal Commodification of Human Beings

open access: yesThe Journal of Humanistic Counseling, EarlyView.
ABSTRACT This article examines the future place of humanistic counseling, assuming the successful mass deployment of artificial intelligence therapy chatbots (AITCs). We systematically identify the limitations of AITCs through the lens of Jean Baudrillard's view on simulacra and hyperreality and identify five collective psychosocial consequences of ...
Brett. D. Wilkinson, Andrew M. Brown
wiley   +1 more source

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