Results 61 to 70 of about 258,672 (295)
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Generalized -Einstein 3-dimensional trans-Sasakian manifold
, 2020 . In the present note we have introduced a new concept called generalized -Einstein manifold in a 3-dimensional trans-Sasakian manifold and have given some preliminary ideas about the same.
Sasakian Manifold +2 more
core
Low-pressure nozzle with aerodynamic fuel atomization
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2020 A research was carried out with the construction of a model of a low-pressure nozzle with aerodynamic fuel atomization, which shows the advantages of nozzles of this type.
S. S. Tihonchik, N. I. Puchko
doaj +1 more source
Quaternionic Structures in Mathematics and Physics, 2001 Almost-complex and hyper-complex manifolds are considered in this paper from the point of view of complex analysis and potential theory. The idea of holomorphic coordinates on an almost-complex manifold $(M,\mathbf{J}%)$ is suggested by D. Spencer.
Dimiev, S., Lazov, R., Milev, N.
openaire +2 more sources
Physics Letters B, 1997 We use non-perturbative U-duality symmetries of type II strings to construct new vacuum solutions. In some ways this generalizes the F-theory vacuum constructions. We find the possibilities of new vacuum constructions are very limited. Among them we construct new theories with N=2 supersymmetry in 3-dimensions and (1, 1) supersymmetry in 2-dimensions.
Kumar, Alok, Vafa, Cumrun
openaire +4 more sources
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Cogent Engineering, 2018 The present-day distributed computing systems are asynchronous in nature, and they cover heterogeneous nodes as well as networks having geographic distribution scale.
Susmit Bagchi
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source