Results 81 to 90 of about 258,672 (295)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Topological Manifolds [PDF]

open access: yesFormalized Mathematics, 2014
Summary Let us recall that a topological space M is a topological manifold if M is second-countable Hausdorff and locally Euclidean, i.e. each point has a neighborhood that is homeomorphic to an open ball of E
openaire   +3 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

SHRINKING A MANIFOLD IN A MANIFOLD [PDF]

open access: yesProceedings of the National Academy of Sciences, 1966
Hocking, J. G., Kwun, K. W.
openaire   +3 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Cohomologies of certain orbifolds [PDF]

open access: yes, 2013
We study the Bott–Chern cohomology of complex orbifolds obtained as a quotient of a compact complex manifold by a finite group of ...
Angella, Daniele
core   +1 more source

Sparse, Robust and Discriminative Representation by Supervised Regularized Auto-encoder

open access: yesInternational Journal of Information and Communication Technology Research, 2019
Recent researches have determined that regularized auto-encoders can provide a good representation of data which improves the performance of data classification.
Nima Farajian
doaj  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Markov-Embedded Affinity Learning with Connectivity Constraints for Subspace Clustering

open access: yesApplied Sciences
Subspace clustering algorithms have demonstrated remarkable success across diverse fields, including object segmentation, gene clustering, and recommendation systems.
Wenjiang Shao, Xiaowei Zhang
doaj   +1 more source

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