Results 171 to 180 of about 44,698 (202)

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Investigating the role of structural wall stress in aortic growth prognosis in acute uncomplicated type B aortic dissection. [PDF]

Biomech Model Mechanobiol
Liu M, Du Y, Cebull HL, Wu Y, Mazlout A, Kalyanasundaram A, Agarwal R, Dong H, Piccinelli M, Oshinski JN, Elefteriades JA, Gleason RL, Leshnower BG.   +12 more
europepmc   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Nuclear quantum effects in molecular liquids across chemical space. [PDF]

Nat Commun
Ugur BE, Webb MA.
europepmc   +1 more source

Real-space diffusion theory from quantum mechanics using analytic continuation. [PDF]

Heliyon
Sigalotti LDG, Rendón O, Luévano JR.
europepmc   +1 more source

Beyond metaphor: quantitative reconstruction of Waddington landscape and exploration of cellular behavior. [PDF]

Brief Bioinform
Han Y, Chen B, Zhang J, Shang X.
europepmc   +1 more source

High-Frame-Rate Echocardiography: A New Frontier in Noninvasive Functional Assessment. [PDF]

J Clin Med
Mashayekhi F, Shahbazi F, Sousa AAA, Liu M, Voigt JU, Caenen A, D'hooge J.   +6 more
europepmc   +1 more source

The optimal grouting area and cable distribution design for guaranteeing roadway stability while considering fluid mechanical effects via the CMOEAD algorithm. [PDF]

Sci Rep
Li P, Guo Y, Cheng Y, Zhang J.
europepmc   +1 more source

Mapping Local Dissipation and Entropy Production in Complex and Active Fluids. [PDF]

J Phys Chem Lett
Desgranges C, Delhommelle J.
europepmc   +1 more source

Hydrodynamical pathways in the phase change of real fluids.

Gallo M, Occhioni F, Daniele R, Casciola C.   +3 more
europepmc   +1 more source