Results 171 to 180 of about 2,254,479 (296)
Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout
Arthritis Care &Research, EarlyView.Objective
Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin +13 morewiley +1 more sourcePharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial
Arthritis Care &Research, EarlyView.Objective
This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods
This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators +14 morewiley +1 more sourceCognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial
Arthritis Care &Research, EarlyView.Objective
Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight +29 morewiley +1 more sourceMycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry
Arthritis Care &Research, EarlyView.Objective
Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of the SPRING Italian Registry Collaborators +77 morewiley +1 more sourceAddressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Arthritis Care &Research, EarlyView.Objective
Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg +8 morewiley +1 more sourceThe Children's Urgent Reduction of Forearm Fractures in the Emergency Department (CURFFED) project : a national prospective trainee-led collaborative audit of practice. [PDF]
Bone Jt OpenGourbault LJ, Whitham R, Womersley A, Jones E, Christie A, Duggleby L, Atherton WG, CURFFED Collaborative, Doughty B, Smith I, Hassan AR, Levitt W, Davies A, Carpenter C, Saltanat S, Buddhdev P, Lennox-Warburton H, Donnelly E, Kim K, Farooq J, Dean CS, Edwards C, Mahmoud M, Stone A, Oyekan A, Jalgaonkar A, To C, Hunt A, Garner M, Campion A, Sison M, Irby S, Price M, Sharoff L, Worley R, Tahir H, Bircher A, Modi N, Theobald E, Genena A, Carter D, Milnes L, Roberts T, Vasudev A, Green D, Boucher A, Caruana E, Khokhar O, Kumar P, Rahman H, Seewoonarain S, Thumbadoo R, Forster S, Vadivelu R, Bagshaw L, Varghese B, Thalanki S, Franco AC, Hamid L, Liew I, Robinson J, Gurung I, Figg P, Moverley R, Neal-Smith G, Barot K, Oo TP, Hanger J, Larsen M, Jones A, Lougher L, Flintoft-Burt M, Dellis S, Kamal T, Bajaj S, Chema K, Lebe M, Bhandari G, Jeans E, James K, Barrow T, Fernandez L, Razemba T, Hawkins R, Anderson K, Tillotson L, Thomas W, Burden E, Kadambande S, Ibrahim IK, O'Boyle M, McCormack L, O'Donnell J, Baird E, MacDonald F, Aithie J, Robinson P, Esland J, Keightley A, Jain A, Thakker D, Nayak M, Caamina L, Barrow T, Discalicau D, Lockton Z, Burgan A, Morris G, Bansal R, Sinha M, Mostafa O, Ishaq U, Elmorsy A, Thomas A, Ross P, Theivendran K, Khaleeq T, Lindisfarne E, Gangadharan R, Thiruchandran G, Youssef K, Tober A, Shah N, Varasteh A, Bajracharya A, Lashin A, Mifsud M, Lloyd T, Kirk C, Ball T, Sheen J, Kapoor S, Jones IT, Donnachie D, Clamp K, Westacott D, Miller J, Hedge E, Gomindes A, Amour L, Ibrahim J, Dwyer J, Bickley M, Fulcher E, Chourasia AK, Hosny S, Hashem M, Dutta A, Leong D, Fergurson K, Haddock A, Malik M, Varasteh A, Cruz L, Jenkins L, East J, Oxley C. +156 moreeuropepmc +1 more source
