Results 61 to 70 of about 28,749 (235)

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Trends in Extreme Climate Indices for Pará State, Brazil

Revista Brasileira de Meteorologia
The present study aimed to analyze trends in air temperature and rainfall for 13 locations in the state of Pará using nonparametric tests. Daily data of maximum and minimum air temperatures and precipitation covering the period 1970-2006, collected by ...
Carlos Antonio Costa dos Santos, Verônica Gabriella de Oliveira   +1 more
doaj   +1 more source

Statistical and anomalies analysis of the 50-year precipitation of the synoptic stations in Iran [PDF]

تحقیقات کاربردی علوم جغرافیایی, 2023
The purpose of this study is to determine the long-term variations in rainfall data as well as to identify wet and dry periods of 35 synoptic stations in Iran.
mina mirian, mostafa karampoor, mohamd moradi, houshang ghemi, behrouz nasiri   +4 more
doaj  

Trend analysis and change point detection of annual and seasonal precipitation and temperature series over southwest Iran [PDF]

, 2014
This paper presents results of trend analysis and change point detection of annual and seasonal precipitation, and mean temperature (TM), maximum temperature (TMAX) and minimum temperature (TMIN) time series of the period 1950-2007.
Dhorde, AG, Kripalani, RH, Zarenistanak, M   +2 more
core   +1 more source

The impact of COVID‐19 pre‐university education on first‐grade medical students. A performance study of students of a Department of Histology

Anatomical Sciences Education, Volume 18, Issue 3, Page 254-263, March 2025.
Abstract The recent coronavirus disease (COVID‐19) forced pre‐university professionals to modify the educational system. This work aimed to determine the effects of pandemic situation on students' access to medical studies by comparing the performance of medical students.
José Manuel García, David Sánchez‐Porras, Miguel Etayo‐Escanilla, Paula Ávila‐Fernández, Olimpia Ortiz‐Arrabal, Miguel‐Ángel Martín‐Piedra, Fernando Campos, Óscar‐Darío García‐García, Jesús Chato‐Astrain, Miguel Alaminos   +9 more
wiley   +1 more source

Variação temporal dos elementos climáticos e da ETo em Catalão, Goiás, no período de 1961-2011

Revista Brasileira de Engenharia Agrícola e Ambiental, 2014
Neste trabalho se avaliou a existência de tendência na distribuição temporal dos elementos do clima e da evapotranspiração de referência para a localidade de Catalão, no estado de Goiás.
Leonidas P. de Alencar, Everardo C. Mantovani, Vinicius B. Bufon, Gilberto C. Sediyama, Thieres G. F. da Silva   +4 more
doaj   +1 more source

Mann–Kendall-Based Concrete Failure Trend Analysis and Its Implementation for Dynamic Building Monitoring

Buildings, 2022
Analyzing monitoring data efficiently is a classic problem in structural health monitoring. A nonparametric test method, the Mann–Kendall (MK) method, was implemented in this study, which is commonly used to detect monotonic trends in a series of ...
Xu Yang, Xueying Han
doaj   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Analysis of the Wind Speed Trend over Iran [PDF]

نشریه جغرافیا و برنامه‌ریزی, 2015
The aim of this study is the analysis of surface wind speed in monthly and annual times scales in Iran using four different versions of the Mann-Kendall method: i) conventional Mann-Kendall method (MK1); ii) Mann-Kendall method following removing the ...
Rasool Mirabbasi Najafabadi, yaghoob Dinpashoh   +1 more
doaj  

A review of applied methods in Europe for flood-frequency analysis in a changing environment [PDF]

, 2013
The report presents a review of methods used in Europe for trend analysis, climate change projections and non-stationary analysis of extreme precipitation and flood frequency.
Kjeldsen, T.R., Lang, M., Lawrence, D., Madsen, H., Martinkova, M.   +4 more
core