The C-type lectin receptor SIGNR3 binds to fungi present in commensal microbiota and influences immune regulation in experimental colitis [PDF]
, 2013 Inflammatory bowel disease is a condition of acute and chronic inflammation of the gut. An important factor contributing to pathogenesis is a dysregulated mucosal immunity against commensal bacteria and fungi.
Eriksson, Magdalena +5 more
core +1 more source
MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis
Journal of Inflammation Research, 2022 Yunzhi Liu,1,2,* Na Zhao,3,* Qishan Xu,1,2 Fan Deng,1 Ping Wang,1,2 Lijun Dong,1,2 Xiao Lu,2 Lihua Xia,3 Mingyong Wang,4 Zhengliang Chen,2 Jia Zhou,2 Daming Zuo1,5 1Department of Medical Laboratory, School of Laboratory Medicine and Biotechnology,
Liu Y +11 more
doaj
Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro [PDF]
, 2018 Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a ...
Borriello, Francesco +7 more
core +1 more source
MBL2 Genetic Variants in HCV Infection Susceptibility, Spontaneous Viral Clearance and Pegylated Interferon Plus Ribavirin Treatment Response [PDF]
, 2016 Hepatitis C is disease that damages the liver, and it is caused by the hepatitis C virus (HCV). The pathology became chronic in about 80% of the cases due to virus persistence in the host organism.
ALBERI, GIULIA +8 more
core +1 more source
Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes
Journal of Diabetes Research, 2017 Objective. Mannan-binding lectin (MBL) concentration in plasma is increased in subjects with type 1 diabetes and associated with increased mortality and risk of diabetic nephropathy.
Gry Høst Dørflinger +4 more
doaj +1 more source
Frontiers in Endocrinology, 2019 Background: Diabetic nephropathy (DN) is the leading cause of end-stage failure of the kidneys; however, its pathogenesis remains unknown. This study assessed the expression of complement components in the kidneys of rats with type 2 DN to investigate ...
Yinqiong Huang +7 more
doaj +1 more source
FEBS Letters, 1999 Mannan‐binding lectin (MBL)‐associated plasma protein (MAp19) is an alternatively spliced form of MBL‐associated serine protease‐2, a component of a complement activation cascade. We observed that MAp19 is excreted in human urine. Interestingly, the amount of MAp19 was higher in urine of renal cell carcinoma patients than healthy people.
Kang, Insug +6 more
openaire +2 more sources
Mannan-Binding Lectin Serum Levels in 593 Healthy Iranian Children and Adults
Iranian Journal of Allergy, Asthma and Immunology, 2014 Mannan-binding lectin (MBL) is a vital protein of innate immune system and has two critical functions: complement activation through the lectin pathway and opsonization.
Sara Zahedifard +8 more
doaj
Frontiers in Psychiatry, 2018 Evidence has accumulated that the occurrence of psychiatric disorders is related to chronic inflammation. In support of this linkage, changes in the levels of circulating pro-inflammatory cytokines and chemokines in the peripheral blood (PB) of ...
Mariusz Z. Ratajczak +7 more
doaj +1 more source
A Novel Evidence That Mannan Binding Lectin (MBL) Pathway of Complement Cascade Activation is Involved in Homing and Engraftment of Hematopoietic Stem Progenitor Cells (HSPCs). [PDF]
Stem Cell Rev Rep, 2020 Adamiak M +4 more
europepmc +1 more source