Results 161 to 170 of about 4,456 (216)

Exploring the intersection of atherosclerosis and Alzheimer's disease: the role of inflammation and complement activation. [PDF]

Inflamm Res
Vataja E, Ratti G, Safa A, Pagano M, Ferrante L, Meri S, Haapasalo K.   +6 more
europepmc   +1 more source

The role of gut mycobiome in responses to cancer immunotherapy. [PDF]

Gut Microbes
Szóstak N, Kozłowski P, Zuo T, Philips A.   +3 more
europepmc   +1 more source

The Role of Complement in the Pathogenesis and Treatment of Myasthenia Gravis. [PDF]

Cells
Martinez Salazar A, Mokhtari S, Peguero E, Jaffer M.   +3 more
europepmc   +1 more source

Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein. [PDF]

Front Immunol
Bally I, Drumont G, Rossi V, Guseva S, Botova M, Reiser JB, Thépaut M, Dergan Dylon S, Dumestre-Pérard C, Gaboriaud C, Fieschi F, Blackledge M, Poignard P, Thielens NM.   +13 more
europepmc   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy. [PDF]

Cancer Med
Li F, Qiao L, Liang X, Zhang Y, Liang N, Xie J, Deng G, Hao Y, Hu P, Wu X, Ding F, Feng C, Mu Y, Zhang J.   +13 more
europepmc   +1 more source

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Recombinant mannan-binding lectin (MBL) for therapy

Biochemical Society Transactions, 2003
Mannan-binding lectin (MBL) is a plasma protein involved in the innate immune response. It binds to a number of micro-organisms and promotes killing of these through complement activation either directly or through opsonization. Clinical evidence indicates that in a variety of situations genetically determined low MBL levels are associated with ...
Jensenius, Jens Christian, Jensen, P H, McGuire, K, Larsen, J L, Thiel, S   +4 more
openaire   +2 more sources

Biochemistry and genetics of mannan-binding lectin (MBL)

Biochemical Society Transactions, 2003
Mannose- or mannan-binding lectin (MBL) is a member of the collectin protein family, which includes lung surfactant proteins SP-A and SP-D. Each member consists of similar or identical polypeptide chains with a region of collagen-like sequence followed by a C-type lectin domain.
J S, Presanis, M, Kojima, R B, Sim
openaire   +2 more sources

Mannan-binding lectin (MBL) serum levels and post-operative infections

Biochemical Society Transactions, 2003
Mannan-binding lectin (MBL) is a central component of the innate immune system. Here we investigated the role of MBL in surgical patients during the peri-operative phase. Basal and post-operative (days 1–3 post-surgery) serum samples were obtained prospectively from 156 patients undergoing major elective gastrointestinal surgery for malignant disease ...
M, Siassi, W, Hohenberger, J, Riese
openaire   +2 more sources

Mannan-binding lectin (MBL) in chickens: molecular and functional aspects

Developmental & Comparative Immunology, 2000
Mannan-binding lectin (MBL) is a serum collectin (i.e. mosaic protein with collagenous and lectin domains) involved in the innate immune defence against various microbes. In vitro studies indicate that MBL exerts its function by binding to the microbial surface through its carbohydrate recognition domains followed by direct opsonization or complement ...
Laursen, S. B., Lerberg Nielsen, O.
openaire   +2 more sources

Genetic influences on mannan‐binding lectin (MBL) and mannan‐binding lectin associated serine protease‐2 (MASP‐2) activity

Genetic Epidemiology, 2006
AbstractThe lectin pathway of the complement system is activated when Mannan‐binding lectin (MBL) in complex with MASP‐2 binds microorganisms. Polymorphisms in both genes are responsible for low serum levels, which associate with increased risk of infection and autoimmune disease.
Sorensen, Grith L, Petersen, Inge, Thiel, Steffen, Fenger, Mogens, Christensen, Kaare, Kyvik, Kirsten O, Sørensen, Thorkild I A, Holmskov, Uffe, Jensenius, Jens Christian   +8 more
openaire   +5 more sources